Results 41 to 50 of about 733,474 (306)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Science Progress, 2020 Urban public transport is a very essential mode for urban residents’ commute travel; however, the unbalanced spatial and temporal distribution of travel demand usually leads to passenger flow congestion risk at certain section and time.
Siyong Ma +4 more
doaj +1 more source
Knowledge evaluation in product lifecycle design and support [PDF]
, 2014 Enterprises are focusing more and more on knowledge issues for global product development. This paper describes knowledge evolution processes in product development activities and proposes a knowledge evaluation method in product lifecycle design.
SUGIMOTO, Shigeo +4 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Formal Medical Knowledge Representation Supports Deep Learning Algorithms, Bioinformatics Pipelines, Genomics Data Analysis, and Big Data Processes. [PDF]
Yearb Med Inform, 2019 To select, present, and summarize the best papers published in 2018 in the field of Knowledge Representation and Management (KRM). A comprehensive and standardized review of the medical informatics literature was performed to select the most interesting ...
Dhombres F +2 more
europepmc +2 more sources
Interpolation in Knowledge Representation
CoRRThe article will appear in Balder ten Cate, Jean Christoph Jung, Patrick Koopmann, Christoph Wernhard and Frank Wolter, editors. Theory and Applications of Craig Interpolation.
Jung, Jean Christoph +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A framework to analyze argumentative knowledge construction in computer-supported collaborative learning [PDF]
, 2006 Computer-supported collaborative learning (CSCL) is often based on written argumentative discourse of learners, who discuss their perspectives on a problem with the goal to acquire knowledge.
Weinberger, Armin, Fischer, Frank
core +1 more source
Compact geometric representation of qualitative directional knowledge [PDF]
, 2020 © 2020 Elsevier B.V. To effectively and efficiently deal with large-scale spatial data is critical for applications in the age of information technology.
Meng, H, Long, Z, Li, T, Li, S
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source