Results 61 to 70 of about 733,474 (306)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Effects of microbial organic fertilizer on nitrogen cycling-related microbial communities and nitrogen-fixing system stability in saline soil

iScience
Summary: Microbial organic fertilizers (MOFs) have shown to improve nitrogen fixation efficiency, particularly under saline or nutrient-stressed conditions.
Peifei Cong, Pengfei Huang, Zhisheng Huang   +2 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Editorial

Advances in Knowledge Representation
A publicação dessa edição especial da revista AKR dedicada ao tema "Um modelo ontológico para o sistema cadastral brasileiro" reflete uma importante e necessária discussão sobre a administração territorial no país.
Suzana Daniela
doaj   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Innovative ways of knowledge representation and management

, 2012
Knowledge is the key for success. The adequate treatment you make on data for generating knowledge can make a difference in projects, processes, and networks.
Zapata Jaramillo, Carlos Mario, González-Calderon, Guillermo   +1 more
core  

Ontologies, Different Reasoning Strategies, Different Logics, Different Kinds of Knowledge Representation: Working Together [PDF]

, 2006
The recent experiences in the building, maintenance and reuse of ontologies has shown that the most efficient approach is the collaborative one. However, communication between collaborators such as IT professionals, librarians, web designers and subject ...
Bosch, Mela
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

What\u27s Important About Knowledge Representation ?

, 1983
This article discusses a number of issues that serve as research goals for discovering the general principles of knowledge representation. Using techniques and concepts evolved while developing the knowledge-representation system KL-One as ...
W. Woods
core  

Knowledge representation issues in control knowledge learning [PDF]

, 2000
Seventeenth International Conference on Machine Learning. Stanford, CA, USA, 29 June-2 July, 2000Knowledge representation is a key issue for any machine learning task.
Borrajo, Daniel, Aler, Ricardo, Borrajo Millán, Daniel, Aler Mur, Ricardo, Isasi, Pedro, Isasi Viñuela, Pedro   +5 more
core