Results 61 to 70 of about 8,829,417 (294)

Editorial

Advances in Knowledge Representation
A publicação dessa edição especial da revista AKR dedicada ao tema "Um modelo ontológico para o sistema cadastral brasileiro" reflete uma importante e necessária discussão sobre a administração territorial no país.
Suzana Daniela
doaj   +4 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bus passenger flow congestion risk evaluation model based on the Pressure-State-Response framework: A case study in Beijing

Science Progress, 2020
Urban public transport is a very essential mode for urban residents’ commute travel; however, the unbalanced spatial and temporal distribution of travel demand usually leads to passenger flow congestion risk at certain section and time.
Siyong Ma, Jiancheng Weng, Chang Wang, Dimitrios Alivanistos, Pengfei Lin   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

What\u27s Important About Knowledge Representation ?

, 1983
This article discusses a number of issues that serve as research goals for discovering the general principles of knowledge representation. Using techniques and concepts evolved while developing the knowledge-representation system KL-One as ...
W. Woods
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Innovative ways of knowledge representation and management

, 2012
Knowledge is the key for success. The adequate treatment you make on data for generating knowledge can make a difference in projects, processes, and networks.
Zapata Jaramillo, Carlos Mario, González-Calderon, Guillermo   +1 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Ontologies, Different Reasoning Strategies, Different Logics, Different Kinds of Knowledge Representation: Working Together [PDF]

, 2006
The recent experiences in the building, maintenance and reuse of ontologies has shown that the most efficient approach is the collaborative one. However, communication between collaborators such as IT professionals, librarians, web designers and subject ...
Bosch, Mela
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source