Results 61 to 70 of about 9,109,199 (294)

Editorial

open access: yesAdvances in Knowledge Representation
A publicação dessa edição especial da revista AKR dedicada ao tema "Um modelo ontológico para o sistema cadastral brasileiro" reflete uma importante e necessária discussão sobre a administração territorial no país.
Suzana Daniela
doaj   +4 more sources

Frameworks for knowledge representation

open access: yes, 2011
Chapter 2: This chapter is directed towards the problem of representation and translation across knowledge systems and frameworks, with a particular focus on those used in the emerging world of the semantic web.
Magee, Liam (R17938), Liam Magee
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Bus passenger flow congestion risk evaluation model based on the Pressure-State-Response framework: A case study in Beijing

open access: yesScience Progress, 2020
Urban public transport is a very essential mode for urban residents’ commute travel; however, the unbalanced spatial and temporal distribution of travel demand usually leads to passenger flow congestion risk at certain section and time.
Siyong Ma   +4 more
doaj   +1 more source

A CIMS-oriented approach to knowledge representation and processing for process planning

open access: yes, 1994
This paper presents a CIMS-oriented approach to knowledge representation and processing for process planning. It includes a knowledge representation scheme, strategy of task decomposition and synthesis, and construction of knowledge base and optimization
Zhang SJ(张士杰)
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A knowledge representation method for modeling rule-based systems

open access: yes, 2010
Knowledge representation has been the critical and intractable issues for a knowledge-based system, especially for complex or large systems. This paper proposes a knowledge representation approach for modeling rule-based systems using the defined fuzzy ...
Jiang B(姜波)   +4 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

A Representation Formalism for Supporting Reuse of Software Engineering Knowledge

open access: yes, 2022
S.61-70 : Ill., Lit.To transfer innovative software technologies into practice and to continuously improve the software quality and productivity, software-related knowledge should be reused.
Tautz, C., Gresse von Wangenheim, C.
core  

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