Results 81 to 90 of about 9,109,199 (294)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Mereocausality & Causal Mereotopology: A New Concept

Advances in Knowledge Representation
. How is causality/causation associated with parthood? And do parts and their whole interact in distinct causal manners? I introduce a novel concept I call ‘mereocausality’ and its cognates, merging two foundational topics in theoretical and practical ...
Robert Rovetto
doaj  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Modelagem semântica para representação de instrumentos musicais:

Advances in Knowledge Representation
Investiga-se, de forma analítica e comparativa, a possibilidade de modelagem semântica para representação de instrumentos musicais, propondo ampliação da interoperabilidade semântica do Museu Virtual de Instrumentos Musicais (MVIM).
Durval Vieira Pereira, Adriana Olinto Ballesté, Cláudio José Silva Ribeiro   +2 more
doaj  

An Extension of Frame-Based Knowledge Representation Schema

This paper presents an overview of frame–based knowledge representation and Structural Modelling approach as well as a new extension of frame–based knowledge representation schema is described.
Grundspeņķis, Jānis, Zeltmate, Ieva
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Dados sintéticos para treinamento de Inteligência Artificial:

Advances in Knowledge Representation
Enquanto os dados reais são coletados de diferentes contextos do mundo real — como a observação de fenômenos diversos ou a interação de pessoas com sistemas e máquinas — os dados sintéticos são gerados por meio da aplicação de diferentes técnicas, com o
Ananda Fernanda de Jesus, Wesley Algarve, José Eduardo Santarem Segundo   +2 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Design and Use of Semantic Resources: Findings from the Section on Knowledge Representation and Management of the 2020 International Medical Informatics Association Yearbook.

, 2020
To select, present, and summarize the best papers in the field of Knowledge Representation and Management (KRM) published in 2019. A comprehensive and standardized review of the biomedical informatics literature was performed to select the most ...
Dhombres, F, Section Editors For The Imia Yearbook Section On Knowledge Representation And, Management, Charlet, J   +2 more
core   +1 more source

A Formal Approach to Ontological Pluralism in Knowledge Representation through Framework-Mediated Classification

Advances in Knowledge Representation
Conceptual models often assume a hegemonic classificatory framework within which alternative ontological perspectives are interpreted as secondary or reduced to matters of belief, rather than recognized as legitimate ontological commitments.
Linair Maria Campos, Nina Gomes Sobral Barcellos D’Almeida, Maria Luiza de Almeida Campos   +2 more
doaj