Results 101 to 110 of about 3,293,562 (272)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Cadastro Territorial Multifinalitário de Belo Horizonte

open access: yesAdvances in Knowledge Representation
Resumo. A criação do Cadastro Territorial de Belo Horizonte teve início em 1974, sob a denominação de Cadastro Técnico Municipal (CTM), com o propósito de atender tanto às demandas tributárias quanto às necessidades de planejamento urbano.
KARLA BORGES   +3 more
doaj  

Interdisciplinarietà e innovazione [PDF]

open access: yesS&F_scienzaefilosofia.it, 2014
Talking about Interdisciplinary means to define methodological ranges and spheres of research which in the progress of Knowledge seem to open wide in a more and more significant way.
Rossella Bonito Oliva
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Um modelo semântico e ontológico para o cadastro territorial brasileiro

open access: yesAdvances in Knowledge Representation
Este trabalho tem como objetivo apresentar e discutir os problemas de interoperabilidade semântica presentes na legislação brasileira, assim como em documentos técnicos, para produção das bases cadastrais brasileiras em apoio ao desenvolvimento de um ...
Suzana Daniela Rocha Santos e Silva   +3 more
doaj  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Mereocausality & Causal Mereotopology: A New Concept

open access: yesAdvances in Knowledge Representation
. How is causality/causation associated with parthood? And do parts and their whole interact in distinct causal manners? I introduce a novel concept I call ‘mereocausality’ and its cognates, merging two foundational topics in theoretical and practical ...
Robert Rovetto
doaj  

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