Results 121 to 130 of about 3,293,562 (272)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Desafios para Geração do Identificador Único de Imóveis Rurais e Urbanos no Cadastro Imobiliário Brasileiro (CIB)

open access: yesAdvances in Knowledge Representation
A Lei Complementar (LC) nº 214, de 16 de janeiro de 2025, ao regulamentar a Reforma Tributária sobre o Consumo (RTC), estabeleceu que todos os imóveis rurais e urbanos deverão ser inscritos, sob identificação única, no Cadastro Imobiliário Brasileiro ...
Stenio Max Lacerda   +3 more
doaj  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Categories Name for Highly Abstract Ontologies: Limitations and Recommendations

open access: yesAdvances in Knowledge Representation
What’s in a name? This paper highlights some limitations of existing category terms for highly abstract ontologies (and similar types of abstraction models), and proposes recommendations.
Robert Rovetto
doaj  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Between Heaven and Earth: The Common Core of Basic Formal Ontology

open access: yesAdvances in Knowledge Representation
This paper critically examines the relationship between Basic Formal Ontology (BFO) and the Common Core Ontologies (CCO), offering a comprehensive discussion of their theoretical foundations, design patterns, and implementation practices.
JOHN BEVERLEY
doaj  

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