Results 121 to 130 of about 8,829,417 (294)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

OntoMuseu - Uma Ontologia de Referência para Catalogação e Padronização de Obras em Museus

Advances in Knowledge Representation
O patrimônio cultural representa um conjunto de bens materiais e imateriais que refletem a memória, a identidade e a história de uma sociedade. No contexto dos museus, gerir tais bens são atividades que exigem estratégias de organização da informação e ...
Rodrigo Hilario da Rocha, Maria das Graças da Silva Teixeira, Daniela Lucas da Silva Lemos   +2 more
doaj  

Tracking biomedical articles along the translational continuum: a measure based on biomedical knowledge representation. [PDF]

Scientometrics, 2023
Li X, Tang X, Lu W.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

O Papel da Identidade Semântica do Conceito com Vistas à Recuperação Inteligente da Informação:

Advances in Knowledge Representation
Discute-se o desenvolvimento de sistemas de recuperação de informação inteligentes capazes de promover a interoperabilidade semântica entre bases de dados distintas e heterogêneas.  Destaca-se  a importância e a viabilidade de estabelecer mecanismos que
Nilson Theobald Barbosa, Maria Luiza de Almeida Campos   +1 more
doaj  

A Deep Learning Model Incorporating Knowledge Representation Vectors and Its Application in Diabetes Prediction. [PDF]

Dis Markers, 2022
Xu H, Zheng Q, Zhu J, Xie Z, Cheng H, Li P, Ji Y.   +6 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

A knowledge representation method for modeling rule-based systems

, 2010
Knowledge representation has been the critical and intractable issues for a knowledge-based system, especially for complex or large systems. This paper proposes a knowledge representation approach for modeling rule-based systems using the defined fuzzy ...
Jiang B(姜波), Shang WL(尚文利), Dan YG(单玉刚), Liu C(刘昶), Yuan J(袁杰)   +4 more
core  

MecCog: a knowledge representation framework for genetic disease mechanism. [PDF]

Bioinformatics, 2021
Kundu K, Darden L, Moult J.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source