Results 111 to 120 of about 9,109,199 (294)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Cultural Context and Multimodal Knowledge Representation: Seeing the Forest for the Trees. [PDF]
Front Psychol, 2022 Cabezas-García M, Reimerink A.
europepmc +1 more source
, 2019 Deep Knowledge Representation is a topic in Knowledge Representation for Machine ...
Paola Di Maio (505866)
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Erratum: Knowledge Representation for Multi-Scale Physiology Route Modeling. [PDF]
Front Neuroinform, 2022 Frontiers Production Office.
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
OntoMuseu - Uma Ontologia de Referência para Catalogação e Padronização de Obras em Museus
Advances in Knowledge RepresentationO patrimônio cultural representa um conjunto de bens materiais e imateriais que refletem a memória, a identidade e a história de uma sociedade. No contexto dos museus, gerir tais bens são atividades que exigem estratégias de organização da informação e ...
Rodrigo Hilario da Rocha +2 more
doaj
Assessing the Need for Semantic Data Integration for Surgical Biobanks-A Knowledge Representation Perspective. [PDF]
J Pers Med, 2022 Brochhausen M +8 more
europepmc +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
O Papel da Identidade Semântica do Conceito com Vistas à Recuperação Inteligente da Informação:
Advances in Knowledge RepresentationDiscute-se o desenvolvimento de sistemas de recuperação de informação inteligentes capazes de promover a interoperabilidade semântica entre bases de dados distintas e heterogêneas. Destaca-se a importância e a viabilidade de estabelecer mecanismos que
Nilson Theobald Barbosa +1 more
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