Results 91 to 100 of about 3,293,562 (272)

Incorporating GAN for Negative Sampling in Knowledge Representation Learning

open access: yes, 2018
Knowledge representation learning aims at modeling knowledge graph by encoding entities and relations into a low dimensional space. Most of the traditional works for knowledge embedding need negative sampling to minimize a margin-based ranking loss ...
Li, Shuangyin, pan, Rong, Wang, Peifeng
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

OntoMuseu - Uma Ontologia de Referência para Catalogação e Padronização de Obras em Museus

open access: yesAdvances in Knowledge Representation
O patrimônio cultural representa um conjunto de bens materiais e imateriais que refletem a memória, a identidade e a história de uma sociedade. No contexto dos museus, gerir tais bens são atividades que exigem estratégias de organização da informação e ...
Rodrigo Hilario da Rocha   +2 more
doaj  

Knowledge Representation and Management 2022: Findings in Ontology Development and Applications. [PDF]

open access: yesYearb Med Inform, 2023
Charlet J   +2 more
europepmc   +1 more source

From knowledge presentation to knowledge representation to knowledge construction: Future directions for hypermedia [PDF]

open access: yes
Relationships between human memory systems and hypermedia systems are discussed with particular emphasis on the underlying importance of associational memory.
Palumbo, David B.
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

O Papel da Identidade Semântica do Conceito com Vistas à Recuperação Inteligente da Informação:

open access: yesAdvances in Knowledge Representation
Discute-se o desenvolvimento de sistemas de recuperação de informação inteligentes capazes de promover a interoperabilidade semântica entre bases de dados distintas e heterogêneas.  Destaca-se  a importância e a viabilidade de estabelecer mecanismos que
Nilson Theobald Barbosa   +1 more
doaj  

Knowledge representation system for assembly using robots [PDF]

open access: yes
Assembly robots combine the benefits of speed and accuracy with the capability of adaptation to changes in the work environment. However, an impediment to the use of robots is the complexity of the man-machine interface. This interface can be improved by
Donath, M., Jain, A.
core   +1 more source

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