Results 71 to 80 of about 8,829,417 (294)

Representation Learning of Knowledge Graphs via Fine-Grained Relation Description Combinations

IEEE Access, 2019
Knowledge representation learning attempts to represent entities and relations of knowledge graph in a continuous low-dimensional semantic space. However, most of the existing methods such as TransE, TransH, and TransR usually only utilize triples of ...
Ming He, Xiangkun Du, Bo Wang
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A study on object-oriented knowledge representation

, 1995
This thesis is a study on object-oriented knowledge representation. The study defines the main concepts of the object model. It also shows pragmatically the use of object-oriented methodology in the development of a concrete software system designed as ...
Salgado-Arteaga, Francisco
core  

Cadastro Territorial Multifinalitário de Belo Horizonte

Advances in Knowledge Representation
Resumo. A criação do Cadastro Territorial de Belo Horizonte teve início em 1974, sob a denominação de Cadastro Técnico Municipal (CTM), com o propósito de atender tanto às demandas tributárias quanto às necessidades de planejamento urbano.
KARLA BORGES, Angelo Neto, Luiz Costa, Flavio Andrade   +3 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Enabling knowledge representation on the Web by extending RDF Schema

, 2001
Recently, a widespread interest has emerged in using ontologies on the Web. Resource Description Framework Schema (RDFS) is a basic tool that enables users to define vocabulary, structure and constraints for expressing meta data about Web resources ...
Broekstra, Jeen, Van Harmelen, Frank; id_orcid, Dieter Fensel, Michel Klein, Klein, Michel, Frank Van Harmelen, Jeen Broekstra, Van Harmelen, Frank, Stefan Decker, Klein, Michel; id_orcid, Ian Horrocks, Fensel, Dieter, Decker, Stefan, Horrocks, Ian   +13 more
core   +1 more source

Um modelo semântico e ontológico para o cadastro territorial brasileiro

Advances in Knowledge Representation
Este trabalho tem como objetivo apresentar e discutir os problemas de interoperabilidade semântica presentes na legislação brasileira, assim como em documentos técnicos, para produção das bases cadastrais brasileiras em apoio ao desenvolvimento de um ...
Suzana Daniela Rocha Santos e Silva, Karla A.V. Borges, Artur C. Brandão, Régis F. Bueno   +3 more
doaj  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Mereocausality & Causal Mereotopology: A New Concept

Advances in Knowledge Representation
. How is causality/causation associated with parthood? And do parts and their whole interact in distinct causal manners? I introduce a novel concept I call ‘mereocausality’ and its cognates, merging two foundational topics in theoretical and practical ...
Robert Rovetto
doaj