Results 41 to 50 of about 2,328,269 (347)

Effectiveness of smoking cessation interventions among adults: an overview of systematic reviews

open access: yesSystematic Reviews
Background This overview of reviews aims to identify evidence on the benefits (i.e. tobacco use abstinence and reduction in smoking frequency) and harms (i.e. possible adverse events/outcomes) of smoking cessation interventions among adults aged 18 years
Mona Hersi   +22 more
doaj   +1 more source

Synthesizing and executing plans in Knowledge and Action Bases [PDF]

open access: yes, 2016
We study plan synthesis for a variant of Knowledge and Action Bases (KABs). KABs have been recently introduced as a rich, dynamic framework where states are full-fledged description logic (DL) knowledge bases (KBs) whose extensional part is manipulated ...
Calvanese, Diego   +3 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Breakthrough Knowledge Synthesis in the Age of Google

open access: yesPhilosophies, 2020
Epistemology is the main branch of philosophy that studies the nature of knowledge, but how is new knowledge created? In this perspective article, I introduce a novel method of knowledge discovery that synthesizes online findings from current and prior ...
Ronald B. Brown
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Global Development of Organic Agriculture: Challenges and Prospects [PDF]

open access: yes, 2006
Preface: Modern agriculture and food systems, including organic agriculture, are undergoing a technological and structural modernization and are faced with a growing globalization.

core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Leveraging Existing Services to Support Evidence Synthesis Researchers Outside of the Health Sciences

open access: yesJournal of Graduate Librarianship, 2023
The author presents a case study for the development of an evidence synthesis service serving researchers outside of the health sciences at a large academic library. The purpose of this project was to highlight the importance of integrating existing core
Elizabeth Kline
doaj   +1 more source

An inclusive and diverse governance structure of the strategy for patient-oriented research (SPOR) Evidence Alliance

open access: yesFACETS, 2022
The Strategy for Patient Oriented Research (SPOR) Evidence Alliance is a research initiative in Canada whose mission is to promote the synthesis, dissemination, and integration of research results into health care and public health decision-making and ...
Carole Lunny   +30 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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