Results 61 to 70 of about 2,328,269 (347)

The Case for a Cooperative Studio Classroom: Teaching Petrology in a Different Way [PDF]

open access: yes, 2005
NOTE: This file size is large, 16.52 mb. This article describes one educator's attempts to modify his Petrology course, changing the lab-lecture format to one that emphasizes studio and cooperative learning.
Dexter Perkins
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence

open access: yesHealth Promotion and Chronic Disease Prevention in Canada
IntroductionWe investigated the prevalence of new or persistent manifestations experienced by COVID-19 survivors at 3 or more months after their initial infection, collectively known as post-COVID-19 condition (PCC ...
Mohamed Kadry Taher   +19 more
doaj   +1 more source

Can ‘digital natives’ be ‘strangers’ to digital technologies? An analytical reflection

open access: yesInkanyiso, 2020
Although a plethora of extant literature categorises them as natives in the digital world, it has been counter-argued that a considerable group of young people cannot be designated as ‘digital natives’.
Theodora D. Adjin-Tettey
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Screening for depression in children and adolescents in primary care or non-mental health settings: a systematic review update

open access: yesSystematic Reviews
Background The transition from childhood to adolescence is associated with an increase in rates of some psychiatric disorders, including major depressive disorder, a debilitating mood disorder.
Andrew Beck   +17 more
doaj   +1 more source

Investigating organic agriculture in a global perspective [PDF]

open access: yes, 2004
The Danish Research Centre for Organic Farming has initiated a knowledge synthesis that will provide an overview of the potential role of organic agriculture in a global perspective. The investigation will be performed by a group of Danish experts from a
Alrøe, Hugo Fjelsted   +1 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

AutoBayes: A System for Generating Data Analysis Programs from Statistical Models

open access: yes, 2003
Data analysis is an important scientific task which is required whenever information needs to be extracted from raw data. Statistical approaches to data analysis, which use methods from probability theory and numerical analysis, are well-founded but ...
Fischer, Bernd, Schumann, Johann
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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