Results 51 to 60 of about 2,328,269 (347)

MILO : a microarchitecture and logic optimizer [PDF]

, 1988
In this report we discuss strengths and weaknesses of logic synthesis systems and describe a system for microarchitectural and logic optimization. Our system uses a set of algorithms for synthesizing SSI/MSI macros from parameterized microarchitecture ...
Gajski, Daniel, Zanden, Nels Vander
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Effectiveness of e-cigarettes as a stop smoking intervention in adults: a systematic review

Systematic Reviews
Background This systematic review aims to identify the benefits and harms of electronic cigarettes (e-cigarettes) as a smoking cessation aid in adults (aged ≥ 18 years) and to inform the development of the Canadian Task Force on Preventive Health Care’s (
Niyati Vyas, Alexandria Bennett, Candyce Hamel, Andrew Beck, Micere Thuku, Mona Hersi, Nicole Shaver, Becky Skidmore, Brian Hutton, Douglas Manuel, Matt Morrow, Smita Pakhale, Justin Presseau, Beverley J. Shea, Julian Little, David Moher, Adrienne Stevens   +16 more
doaj   +1 more source

Providing valid evidence for decision-making: the Drug Safety and Effectiveness Network Methods and Applications Group in Indirect Comparisons (DSEN MAGIC)

FACETS, 2022
In 2009, the Canadian Institutes of Health Research, Health Canada, and other stakeholders established the Drug Safety and Effectiveness Network (DSEN) to address the paucity of information on drug safety and effectiveness in real-world settings.
Sharon E. Straus, Brian Hutton, David Moher, Shannon E. Kelly, George A. Wells, Andrea C. Tricco   +5 more
doaj   +1 more source

Bridges Structural Health Monitoring and Deterioration Detection Synthesis of Knowledge and Technology [PDF]

, 2010
INE/AUTC 10 ...
Dong, Yangtao, Liu, Helen, Song, Ruiqiang   +2 more
core  

Germination: a means to improve the functionality of oat [PDF]

, 2004
The biochemical and physiological reactions of germination have long been utilised to produce barley malt for brewing and other purposes. Also some oat malt has been produced as raw-material of ale and stout production.
Kaukovirta-Norja, Anu, Poutanen, Kaisa, Wilhelmson, Annika   +2 more
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Challenges and Facilitators for Physicians and Medical Schools to Promote Social Accountability in Rural Communities: A Scoping Review and Thematic Analysis

Journal of Medical Education and Curricular Development
Background Social accountability aligns the health demands and priorities of the community and the commitment of medical schools. Existing literature has proposed contextually distinctive interventions encompassing geographical initiatives, institutions ...
Aghna Wasim, Ali Abud, Yihan Wang, Ehsan Tavakoli, Athena Moreno-Gris, Samar Joshi, Arthur Wang, Angela Neasadurai, Nikki Shaw   +8 more
doaj   +1 more source

COVID-19 impact on AMR: a rapid scoping review, equity analysis and evidence gap map study

BMJ Global Health
Introduction The COVID-19 pandemic is expected to have impacted many drivers of antimicrobial resistance (AMR) and compounded existing societal and health inequities.
Susan Rogers Van Katwyk, Mathieu J P Poirier, Becky Skidmore, Ebiowei Samuel F Orubu, Kawsari Abdullah, Fiona Emdin, Kayla Strong, Nicole Shaver, Gideon Asamoah, Emilie Chan   +9 more
doaj   +1 more source

Adverse Events Reporting of Clinical Trials in Exercise Oncology Research (ADVANCE): Protocol for a Scoping Review

Frontiers in Oncology, 2022
IntroductionAdequate, transparent, and consistent reporting of adverse events (AEs) in exercise oncology trials is critical to assess the safety of exercise interventions for people following a cancer diagnosis.
Hao Luo, Hao Luo, Oliver Schumacher, Oliver Schumacher, Daniel A. Galvão, Daniel A. Galvão, Robert U. Newton, Robert U. Newton, Dennis R. Taaffe, Dennis R. Taaffe   +9 more
doaj   +1 more source