Results 71 to 80 of about 2,328,269 (347)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Knowledge synthesis research: a bibliometric analysis

Journal of Clinical Epidemiology, 2016
The purpose of this article is to describe the volume and attributes of original research available in PubMed on emerging knowledge synthesis methods (excluding traditional systematic reviews) published by researchers.Bibliometric analysis.Six-hundred eight studies related to the topic of knowledge synthesis methods were analyzed.
Perrier, Laure, Lightfoot, David, Kealey, M Ryan, Straus, Sharon E, Tricco, Andrea C   +4 more
openaire   +3 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The spectrum of knowledge synthesis methods: From big picture overview to targeted deep dive

Bangabandhu Sheikh Mujib Medical University Journal
Not ...
Tanvir C Turin, Nashit Chowdhury
doaj   +1 more source

Trilostane in dogs [PDF]

, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza, Angles, Baker, Barker, Bell, Benchekroun, Biller, Boag, Braddock, Cerundolo, Chapman, Clemente, Dewis, Dunn, Eastwood, Feldman, Galac, Galac, Golden, Goy-Thollot, Guptill, Hurley, Ian K. Ramsey, Kenefick, Kintzer, Komanicky, Leone, Lorenz, Machida, Mantis, McGee, McGowan, McGrotty, Neiger, Neiger, Neuman, Peterson, Potts, Puddefoot, Ramsey, Ramsey, Randolph, Reusch, Robinson, Ruckstuhl, Semple, Semple, Sieber-Ruckstuhl, Sieber-Ruckstuhl, Skelly, Tebb, Teshima, Tueni, Vaughan, Wenger, Wilbur, Williams, Winterberg, Witt, Zeugswetter   +59 more
core   +1 more source

Unveiling knowledge structure and research trends in human libraries: A systematic synthesis of bibliometric, thematic, and content analysis [PDF]

, 2022
Fung-Mei, Chiao-Min
openalex   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Knowledge synthesis: Animal health and welfare in organic pig production - Final Report COREPIG [PDF]

, 2011
This report reviews the available information on the welfare of pigs when maintained according to organic standards in Europe. It begins by overviewing the populations of organic pigs in different countries at the time of writing (2007), the organic ...
Bochicchio, David, Bonde, Marianne, Edwards, Sandra, Früh, Barbara, Hegelund, Lene, Heinonen, Mari, Leeb, Christine, Lindgren, Kristina, Lubac, Stanislas, Maupertuis, F., Mejer, Helena, Prunier, Armelle, Roepstorff, Allan, Rousing, Tine, Sundrum, Albert, Sundrum, Albert, Werne, Steffen, Wiberg, Sophia   +17 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Outcomes and Characteristics of Interdisciplinary Self-Management Interventions for Older Adults Living with Chronic Pain: Insights from a Scoping Review

Journal of Ageing and Longevity
Introduction: Up to 50% of community-dwelling older adults report living with some chronic pain that interferes with their daily functioning and leads to disabilities.
Samuel Turcotte, Marie-Ève Lapointe, Carolann Shea, Jacqueline Rousseau, Julie Masse, Johanne Higgins, Pierre Rainville, David Lussier, François Dubé, Catherine Genest, Kami Sarimanukoglu, Lucile Agarrat, Maria Varganici, Johanne Filiatrault   +13 more
doaj   +1 more source