Results 71 to 80 of about 826,489 (261)

Growth, Residential Distribution, and Land Price in an Integrated Solow’s Growth and Alonso’s Residential Model [PDF]

, 2018
This study builds a spatial growth model with residential distribution. The model is a synthesis of the Solow growth and Alonso residential models with endogenous land value.
Zhang, Wei-Bin
core   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The spectrum of knowledge synthesis methods: From big picture overview to targeted deep dive

Bangabandhu Sheikh Mujib Medical University Journal
Not ...
Tanvir C Turin, Nashit Chowdhury
doaj   +1 more source

Toward Integration of Knowledge Creation Theories By Primitives Synthesis Through Reflective Verification [PDF]

, 2007
In this paper, we present a way to integrate knowledge creation theories by primitives synthesis, where we extract basic concepts (i.e. primitives) from several existing knowledge creation and management theories, and combine them into a single framework
Sugiyama, Kozo, Meyer, Bertolt
core  

DFM synthesis approach based on product-process interface modelling. Application to the peen forming process. [PDF]

, 2010
Engineering design approach are curently CAD-centred design process. Manufacturing information is selected and assessed very late in the design process and above all as a reactive task instead of being proactive to lead the design choices. DFM appraoches
F. Cochennec, El Gueder, Jawhar, ROUCOULES, Lionel, L. Roucoules, COCHENNEC, Florent, ROUHAUD, Emmanuelle, J. Elgueder, ELGUEDER, Jawhar, E. Rouhaud   +8 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Actionable climate knowledge: from analysis to synthesis [PDF]

, 2006
The traditional reductionist approach to science has a tendency to create `islands of knowledge in a sea of ignorance¿, with a much stronger focus on analysis of scientific inputs rather than synthesis of socially relevant outcomes.
Meinke, H.B., Baethgen, Walter, Kokic, Phil, Baethgen, W., Nelson, Rohan, Stone, Roger, Meinke, H., Kokic, P, Kokic, P., Stone, R., Selvaraju, R., Baethgen, W, Nelson, R., Selvaraju, Ramasamy, Selvaraju, R, Meinke, Holger, Meinke, H, Nelson, R   +17 more
core   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Outcomes and Characteristics of Interdisciplinary Self-Management Interventions for Older Adults Living with Chronic Pain: Insights from a Scoping Review

Journal of Ageing and Longevity
Introduction: Up to 50% of community-dwelling older adults report living with some chronic pain that interferes with their daily functioning and leads to disabilities.
Samuel Turcotte, Marie-Ève Lapointe, Carolann Shea, Jacqueline Rousseau, Julie Masse, Johanne Higgins, Pierre Rainville, David Lussier, François Dubé, Catherine Genest, Kami Sarimanukoglu, Lucile Agarrat, Maria Varganici, Johanne Filiatrault   +13 more
doaj   +1 more source

Games of/against Racial Privilege and Marginalization: A Research Synthesis [PDF]

Game studies is an interdisciplinary field of academic research that draws insights from across the humanities, social sciences, and arts to bring attention to the issues outlined here. As a Knowledge Synthesis project, “Games of/against Racial Privilege
McLaren, Jackson, Oropeza, E, Bird, Ashlee, Voorhees, Gerald, Gray, Kishonna, Whitson, Jennifer   +5 more
core