Results 91 to 100 of about 2,328,269 (347)

A Foundation for Online Knowledge Mobilization in Child and Youth Mental Health: Synthesis Report [PDF]

, 2014
Navigating the online environment to find mental health can be a daunting task, especially for children and youth. Three research projects commissioned by the Mental Health Commission of Canada were summarized in this report. The projects sought insights

core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Global environmental knowledge synthesis: What’s in it for national action?

Sustainability: Science, Practice, & Policy
Global environmental assessments (GEAs) support international environmental governance by synthesizing state-of-the-art scientific knowledge. Increasingly, they also articulate solutions to environmental risks.
Salla Rantala, Jason Jabbour, Juuli Närhi   +2 more
doaj   +1 more source

Relation of Vegetarian Dietary Patterns With Major Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

Frontiers in Nutrition, 2019
Background: Vegetarian dietary patterns are recommended for cardiovascular disease (CVD) prevention and management due to their favorable effects on cardiometabolic risk factors, however, the role of vegetarian dietary patterns in CVD incidence and ...
Andrea J. Glenn, Andrea J. Glenn, Andrea J. Glenn, Effie Viguiliouk, Effie Viguiliouk, Effie Viguiliouk, Maxine Seider, Maxine Seider, Maxine Seider, Beatrice A. Boucher, Tauseef A. Khan, Tauseef A. Khan, Tauseef A. Khan, Sonia Blanco Mejia, Sonia Blanco Mejia, Sonia Blanco Mejia, David J. A. Jenkins, David J. A. Jenkins, David J. A. Jenkins, David J. A. Jenkins, David J. A. Jenkins, David J. A. Jenkins, Hana Kahleová, Hana Kahleová, Dario Rahelić, Dario Rahelić, Jordi Salas-Salvadó, Jordi Salas-Salvadó, Cyril W. C. Kendall, Cyril W. C. Kendall, Cyril W. C. Kendall, Cyril W. C. Kendall, John L. Sievenpiper, John L. Sievenpiper, John L. Sievenpiper, John L. Sievenpiper, John L. Sievenpiper   +36 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Genomic Information for Clinicians in the Electronic Health Record: Lessons Learned From the Clinical Genome Resource Project and the Electronic Medical Records and Genomics Network

Frontiers in Genetics, 2019
Genomic knowledge is being translated into clinical care. To fully realize the value, it is critical to place credible information in the hands of clinicians in time to support clinical decision making.
Marc S. Williams, Casey Overby Taylor, Casey Overby Taylor, Nephi A. Walton, Scott R. Goehringer, Samuel Aronson, Robert R. Freimuth, Luke V. Rasmussen, Eric S. Hall, Cynthia A. Prows, Wendy K. Chung, Alexander Fedotov, Jordan Nestor, Chunhua Weng, Robb K. Rowley, Georgia L. Wiesner, Gail P. Jarvik, Guilherme Del Fiol   +17 more
doaj   +1 more source

Knowledge Synthesis in Health, Wellness and Social Care Research: The Fundamentals of Conducting Comprehensive Reviews

, 2022
Mashrur Kazi, Nashit Chowdhury, Mohammad Chowdhury, Tanvir Chowdhury Turin   +3 more
openalex   +2 more sources

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

Arthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk, Jing Li, Cathy Nasrallah, Cherish Wilson, Alicia Hamblin, Christine Hariz, Cammie Young, Stephen Shiboski, Emma Kersey, Mary Nakamura, Judith F. Ashouri, Mehrdad Matloubian, Andrew J. Gross, Jennifer Barton, Beth Berrean, Jonathan Prugh, Jinoos Yazdany   +16 more
wiley   +1 more source

Citizen Science Approach for Searching and Curating Literature on the Effects of Spaceflight on Cardiovascular Outcomes in Rodents and Humans

Citizen Science: Theory and Practice
The spaceflight environment affects the structure and function of the cardiovascular system, including fluid redistribution, alterations in blood pressure, and changes in cardiac output.
Mattias Neset, Ryan T. Scott, S. Anand Narayanan, Svetlana V. Komarova   +3 more
doaj   +1 more source