Results 91 to 100 of about 8,134,950 (298)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Accuracy-based scoring for phrase-based statistical machine translation [PDF]

, 2010
Although the scoring features of state-of-the-art Phrase-Based Statistical Machine Translation (PB-SMT) models are weighted so as to optimise an objective function measuring translation quality, the estimation of the features themselves does not have ...
Galron, Daniel, Way, Andy, Penkale, Sergio, Ma, Yanjun   +3 more
core   +1 more source

A Living Educational Theory of Knowledge Translation: Improving Practice, Influencing Learners, and Contributing to the Professional Knowledge Base [PDF]

, 2013
This paper captured our joint journey to create a living educational theory of knowledge translation (KT). The failure to translate research knowledge to practice is identified as a significant issue in the nursing profession.
Johnston, Jan, Vickers-Manzin, Jen
core  

Knowledge translation for effective consumers

, 2007
With the emergence of patient-centered care, consumers are becoming more effective managers of their care - in other words, "effective consumers." To support patients to become effective consumers, a number of strategies to translate knowledge to action (
Santesso, N. A., Driedger, S. M., Peter S Tugwell, Qualman, A., Andrew J Wilson, Tugwell, P. S., Brooks, P. M., Tugwell, Peter, Santesso, Nancy, Wilson, A. J., Wale, J., Wells, G. A., O'Connor, Annette, O'Connor, A. M., Gallois, C., Wilson, Andrew, Annette M O’connor, Nancy A Santesso   +17 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Patients’ experiences while undergoing high-intensity gait training during inpatient stroke rehabilitation: a qualitative study

BMC Health Services Research
Background High-intensity gait training is an evidence-based intervention for improving walking outcomes after stroke, but little is known about how patients experience this intervention during inpatient rehabilitation. Understanding patient perspectives
Jennifer L. Moore, Julia A. Mbalilaki, Stein A. Rimehaug, Siri N. Tveitan, Anne-Margrethe Linnestad, Pia Krøll, Simen Lundberg, Marianne Molle, Ingvild Lilleheie   +8 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Combining multi-domain statistical machine translation models using automatic classifiers [PDF]

, 2010
This paper presents a set of experiments on Domain Adaptation of Statistical Machine Translation systems. The experiments focus on Chinese-English and two domain-specific corpora. The paper presents a novel approach for combining multiple domain-trained
Li, Baoli, Banerjee, Pratyush, Way, Andy, Kumar Naskar, Sudip, van Genabith, Josef, Du, Jinhua   +5 more
core   +2 more sources

What is Translation? [PDF]

, 2020
As the translation scholar Michael Cronin states, “if we want a world that values diversity of perspective over the certainty of singular belief, a world where many voices balance the privileged few, then translators must be part of the dialogue” (Eco ...
Johnson, Amber C
core   +1 more source