Results 81 to 90 of about 8,134,950 (298)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Perceptions of Pediatric Nephrologists regarding Timing of Dialysis Initiation in Children in Canada

Canadian Journal of Kidney Health and Disease, 2016
Background: Significant practice variation exists in Canada with respect to timing of dialysis initiation in children. In the absence of evidence to guide practice, physicians' perceptions may significantly influence decision-making.
Jeremy A. Saban, Michael Zappitelli, Susan M. Samuel, Manish M. Sood, R. Todd Alexander, Steven Arora, Robin L. Erickson, Kristine Kroeker, Braden J. Manns, Allison B. Dart   +9 more
doaj   +1 more source

Pregnant women’s views on how to promote the use of a decision aid for Down syndrome prenatal screening: a theory-informed qualitative study

BMC Health Services Research, 2018
Background For pregnant women and their partners, the decision to undergo Down syndrome prenatal screening is difficult. Patient decision aids (PtDA) can help them make an informed decision.
Titilayo Tatiana Agbadjé, Matthew Menear, Michèle Dugas, Marie-Pierre Gagnon, Samira Abbasgholizadeh Rahimi, Hubert Robitaille, Anik M. C. Giguère, François Rousseau, Brenda J. Wilson, France Légaré   +9 more
doaj   +1 more source

The Knowledge Broker's “Fit” in the World of Knowledge Translation [PDF]

Physiotherapy Canada, 2014
Evidence-informed practice (EIP) is a challenge. Success requires facilitators at multiple levels: the individual clinician (e.g., skills for accessing and appraising literature); the organization (e.g., providing resources for training and protected time); professional and regulatory bodies (e.g., need for consensus on standards of practice and ...
Alison M, Hoens, Linda C, Li
openaire   +2 more sources

WordNet gloss translation for under-resourced languages using multilingual neural machine translation

, 2019
In this paper, we translate the glosses in the English WordNet based on the expand approach for improving and generating wordnets with the help of multilingual neural machine translation. Neural Machine Translation (NMT) has recently been applied to many
McCrae, John P., Chakravarthi, Bharathi Raja, Arcan, Mihael   +2 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Improving a Catalan-Spanish statistical translation system using morphosyntactic knowledge [PDF]

, 2009
Comunicació presentada a la 13th Annual Conference of the European Association for Machine Translation, celebrada a Barcelona (Espanya) els dies 14 i 15 de maig del 2009.In this paper, a human evaluation of a Catalan-Spanish Ngram-based statistical ...
Costa-jussà, Marta R., Poch, Marc, Mariño Acebal, José B., Hernández, Adolfo, Farrús, Mireia   +4 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Establishing Effective Patient Engagement Through a Terms of Reference to Foster Inclusivity and Empowerment in Research: Example From a Healthcare Transition Quality Indicators Project

Health Expectations
Introduction Patient engagement in research aims to foster meaningful partnerships, integrating patient experiences into the research process. This paper describes the development of a Terms of Reference (ToR) to support these meaningful partnerships ...
Sarah E. P. Munce, Tomisin John, Dorothy Luong, Sarah Mooney, Lisa Stromquist, Kyle Chambers, Marilyn Crabtree, Sanober Diaz, Gina Dimitropoulos, Megan Henze, Amanda Higgins, Elaine Li, Samadhi Mora Severino, Melanie Penner, Jacklynn Pidduck, Michelle Wan, Laura Williams, Darryl Yates, Alene Toulany   +18 more
doaj   +1 more source

The Qualities of Literary Machine Translation

, 2022
This paper argues that an essential element affecting literary translation – the structure of narrative discourse – has been overlooked in research on literary MT systems so far.
Taivalkoski-Shilov Kristiina
core