Results 101 to 110 of about 1,237,825 (275)

Knowledge translation in global health.

open access: yesBulletin of the World Health Organization, 2005
The Ministerial Summit on Health Research in November 2004 and the World Health Assembly in May 2005 called for more research in developing countries to strengthen health systems and to help achieve the Millennium Development Goals (MDGs) by 2015. Research we believe has to be a component of a strategic process rather than an end in itself.
Peter Tugwell   +4 more
openaire   +4 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

On Yao's method of translation [PDF]

open access: yes, 2002
Machine Translation, i.e., translating one kind of natural language to another kind of natural language by using a computer system, is a very important research branch in Artificial Intelligence.
Hoede, C., Liu, X.
core   +1 more source

RPNet: an End-to-End Network for Relative Camera Pose Estimation

open access: yes, 2018
This paper addresses the task of relative camera pose estimation from raw image pixels, by means of deep neural networks. The proposed RPNet network takes pairs of images as input and directly infers the relative poses, without the need of camera ...
D Nistér   +6 more
core   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Sustaining knowledge translation interventions for chronic disease management in older adults: protocol for a systematic review and network meta-analysis

open access: yesSystematic Reviews, 2018
Background Failure to sustain knowledge translation (KT) interventions impacts patients and health systems, diminishing confidence in future implementation.
Andrea C. Tricco   +24 more
doaj   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

How do clinicians use implementation tools to apply breast cancer screening guidelines to practice?

open access: yesImplementation Science, 2018
Background Implementation tools (iTools) may enhance uptake of guidelines. However, little evidence exists on their use by primary care clinicians. This study explored which iTools clinicians used and how often; how satisfied clinicians were with the ...
Heather Armson   +4 more
doaj   +1 more source

Museums as disseminators of niche knowledge: Universality in accessibility for all [PDF]

open access: yes, 2019
Accessibility has faced several challenges within audiovisual translation Studies and gained great opportunities for its establishment as a methodologically and theoretically well-founded discipline. Initially conceived as a set of services and practices
Rizzo A
core  

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

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