Results 101 to 110 of about 497,473 (309)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Automatic detection of accommodation steps as an indicator of knowledge maturing [PDF]
, 2011 Jointly working on shared digital artifacts – such as wikis – is a well-tried method of developing knowledge collectively within a group or organization.
Moskaliuk, Johannes +13 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
System quality, user satisfaction and end user development
, 1999 Organisations rely heavily on user developed applications (UDAs) to support organisational decision making, but for the most part the satisfaction of the user developer is the sole indicator of application success.
Payne, C. +6 more
core
User Knowledge Creation in Universal Design Processes
, 2016 Besides the need for designers to build a strong body of user knowledge within the domain of Universal Design (UD), linking knowledge about user needs and design practice is fundamental for increasing its uptake.
Ielegems, Elke +5 more
core +1 more source
Comparing Data-Driven Methods for Extracting Knowledge from User Generated Content
Journal of Open Innovation: Technology, Market and Complexity, 2019 This study aimed to compare two techniques of business knowledge extraction for the identification of insights related to the improvement of digital marketing strategies on a sample of 15,731 tweets.
Jose Ramon Saura +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
An investigation of end user development success
, 2002 User development of applications provides end users with an alternative to the traditional process of systems development by allowing them to solve job related problems by developing their own software applications.
McGill, Tanya Jane
core
Self-organising management of user-generated data and knowledge [PDF]
, 2014 The proliferation of sensor networks, mobile and pervasive computing has provided the technological push for a new class of participatory-sensing applications, based on sensing and aggregating user-generated content, and transforming it into knowledge ...
Macbeth, S +3 more
core +1 more source
MATEC Web of Conferences, 2018 In order to solve the lack of knowledge relevance and topic drift in traditional keyword search, this paper proposed knowledge extraction strategy based knowledge point association and recognition of user intention based user intention theme map and the ...
Yang Zhen
doaj +1 more source