Flywheel proof mass actuator for active vibration control [PDF]
, 2023 This paper presents the experimental results of a new proof mass actuator for the implementation of velocity feedback control loops to reduce the flexural vibration of a thin plate structure.
Kras A., Gardonio P.
core +1 more source
KRAS mutation analysis by PCR : a comparison of two methods [PDF]
, 2015 Background: KRAS mutation assays are important companion diagnostic tests to guide anti-EGFR antibody treatment of metastatic colorectal cancer. Direct comparison of newer diagnostic methods with existing methods is an important part of validation of ...
Lucas, Katie +9 more
core +2 more sources
Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials [PDF]
, 2012 Purpose: This study investigated the impact of specific mutations in codon 12 of the Kirsten-ras (KRAS) gene on treatment efficacy in patients with metastatic colorectal cancer (mCRC).
Zielinski, Christoph C. +12 more
core +1 more source
Deep sequence analysis of non-small cell lung cancer: Integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations [PDF]
, 2012 KRAS mutations are highly prevalent in non-small cell lung cancer (NSCLC), and tumors harboring these mutations tend to be aggressive and resistant to chemotherapy.
David Rossell +65 more
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Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]
, 2012 Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
Göke, Burkhard +32 more
core +2 more sources
Active vibration control unit with a flywheel inertial actuator
, 2020 This paper presents simulation and experimental results on the implementation of a velocity feedback control unit with a new flywheel inertial actuator, which can be used to reduce flexural vibration of distributed structures. The actuator incorporates
Kras A., Gardonio P.
core +1 more source
MAPK and AKT pathway inactivation by cetuximab-KRAS- and cetuximab-PIK3CA-esiRNA treatment.
, 2018 Tumor lysate samples from xenograft experiments were processed for SDS PAGE and probed in Western blots for expression of KRAS downstream MAPK pathway effector phospho-ERK and PIK3CA downstream phospho-AKT along with their unphosphorylated (total ...
Wolfgang Hartmann (38453) +9 more
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Targeting PDE6D for inhibiting KRAS: A computational approach [PDF]
, 2022 Lung cancer is the cancer of the lung\u27s epithelial cells typically characterized by difficult breathing, chest pain, blood-stained coughs, headache, and weight loss. If left unmanaged, lung cancer can spread to other body parts.
Gbenga, Dairo +3 more
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Validation of Pyrosequencing for the Analysis of KRAS Mutations in Colorectal Cancer [PDF]
, 2013 The use of antibodies against epidermal growth factor receptor( EGFR) in conjunction with conventionalchemotherapy for metastatic colorectal cancer (CRC) in patients with KRAS wild-type tumors has beenproven to be efficacious.
Akimoto, Naohiko +8 more
core
Velocity feedback control with a flywheel proof mass actuator
, 2017 This paper presents four new proof mass actuators to be used in velocity feedback control systems for the control of vibrations of machines and flexible structures.
KRAS, Aleksander Stefan +3 more
core +1 more source