Results 1 to 10 of about 3,599 (242)

Istra kroz željezno doba

Arheološki Vestnik, 2021
[Istra v železni dobi] Predstavljen je kratek pregled arheoloških raziskav železne dobe v Istri, od začetkov v 19. stoletju do najnovejših arheoloških izkopavanj. Ob tem je poudarjen doprinos prof.
Kristina Mihovilić
doaj   +5 more sources

Evaluating the impact of adjunctive istradefylline on the cumulative dose of levodopa-containing medications in Parkinson's disease: study protocol for the ISTRA ADJUST PD randomized, controlled study. [PDF]

BMC Neurol, 2022
Background Levodopa remains the most effective symptomatic treatment for Parkinson’s disease (PD) more than 50 years after its clinical introduction. However, the onset of motor complications can limit pharmacological intervention with levodopa, which ...
Hatano T, Kano O, Sengoku R, Yoritaka A, Suzuki K, Nishikawa N, Mukai Y, Nomura K, Yoshida N, Seki M, Matsukawa MK, Terashi H, Kimura K, Tashiro J, Hirano S, Murakami H, Joki H, Uchiyama T, Shimura H, Ogaki K, Fukae J, Tsuboi Y, Takahashi K, Yamamoto T, Yanagisawa N, Nagayama H.   +25 more
europepmc   +2 more sources

Ponorni kontaktni kras Zrenjskega ravnika, Istra, Hrvaška

Dela, 2022
Zrenjski ravnik je kraška uravnava v severni Istri na Hrvaškem, ki ima na severnem in južnem robu obsežna območja ponornega kontaktnega krasa. Vodotoki pritekajo z eocenskih klastičnih kamnin in ponikajo v zakrasele karbonatne kamnine pretežno kredne ...
Uroš Stepišnik
doaj   +2 more sources

Involvement of Adenosine A₂A Receptors in Anxiety-Like Behaviors in Tetrahydrocannabinol-Treated Mice. [PDF]

Brain Behav
This study evaluated anxiety‐like behavior in mice across treatment and control groups using open field and elevated plus maze tests, followed by hippocampal receptor gene expression analysis. The combined behavioral and molecular data identify potential receptor‐level mechanisms underlying the observed treatment‐associated behavioral changes. ABSTRACT
Ün B, Akarsakarya Z, Özü ÖY, Ilgaz NS, Yılmaz MB, Seçilmiş D, Seçilmiş MA.   +6 more
europepmc   +2 more sources

Impact of istradefylline on motor and non-motor symptoms in patients with Parkinson's disease: Subanalysis of the ISTRA ADJUST PD. [PDF]

Clin Park Relat Disord
Highlights • In Parkinson’s patients, off episode symptoms do not fully improve with levodopa.• Istradefylline is an adjunct to levodopa for patients experiencing off episodes.• Istradefylline improved motor and non-motor symptoms in a controlled ...
Nagayama H, Kano O, Sengoku R, Yanagisawa N, Yoritaka A, Suzuki K, Nishikawa N, Mukai Y, Nomura K, Yoshida N, Seki M, Matsukawa MK, Terashi H, Kimura K, Tashiro J, Hirano S, Murakami H, Joki H, Uchiyama T, Shimura H, Ogaki K, Fukae J, Tsuboi Y, Takahashi K, Yamamoto T, Kaida K, Ihara R, Kanemaru K, Hatano T.   +28 more
europepmc   +2 more sources

Impact of Istradefylline on Levodopa Dose Escalation in Parkinson's Disease: ISTRA ADJUST PD Study, a Multicenter, Open-Label, Randomized, Parallel-Group Controlled Study. [PDF]

Neurol Ther
A higher levodopa dose is a risk factor for motor complications in Parkinson’s disease (PD). Istradefylline (IST) is used as adjunctive treatment to levodopa in PD patients with off episodes, but its impact on levodopa dose titration remains unclear. The
Hatano T, Sengoku R, Nagayama H, Yanagisawa N, Yoritaka A, Suzuki K, Nishikawa N, Mukai Y, Nomura K, Yoshida N, Seki M, Matsukawa MK, Terashi H, Kimura K, Tashiro J, Hirano S, Murakami H, Joki H, Uchiyama T, Shimura H, Ogaki K, Fukae J, Tsuboi Y, Takahashi K, Yamamoto T, Kaida K, Ihara R, Kanemaru K, Kano O.   +28 more
europepmc   +2 more sources

Targeting Adenosine A2b Receptor Promotes Penile Rehabilitation of Refractory Erectile Dysfunction. [PDF]

Adv Sci (Weinh)
The A2b receptor of adenosine mediates adenosine‐induced penile erection, rather than the A1, A2a, and A3 receptors. Activating the A2b receptor promotes penile rehabilitation of refractory ED by alleviating hypoxia and fibrosis. Dipyridamole, an oral adenosine transporter inhibitor, can promote penile rehabilitation by attenuating hypoxia and fibrosis,
Xiong Y, Qin F, Wei S, Yang X, Li J, Wu C, Zhang F, Yuan J.   +7 more
europepmc   +2 more sources

Analytical and Clinical Validation of Solo-Test Driver: A Targeted Amplicon-Based NGS Test-System for FFPE and cfDNA Analysis in Clinical Oncology Setting. [PDF]

J Clin Lab Anal
With the growing demand for compact next‐generation sequencing (NGS) test systems tailored to meet key needs in oncology, the Solo‐test Driver panel serves as a valuable tool for companion diagnostics of solid tumors, demonstrating high reliability, sensitivity, and specificity in line with established guidelines. In this work, we outline the framework
Ivanov M, Lebedeva A, Belova E, Grigoreva T, Veselovsky E, Kavun A, Taraskina A, Kuznetsova O, Nikulin V, Belyaeva L, Kravchuk D, Lisitsa T, Barinov A, Pospekhova N, Aliyarova S, Khomenko E, Tryakin A, Demidova I, Stroganova A, Fedyanin M, Mileyko V.   +20 more
europepmc   +2 more sources

Cardiopulmonary resuscitation performed by trained providers and shorter time to emergency medical team arrival increased patients' survival rates in Istra County, Croatia: a retrospective study. [PDF]

Croat Med J, 2019
Aim To assess the effect of the time for emergency medical services (EMS) arrival on resuscitation outcome in the transition period of the EMS system in Istra County.
Bakran K, Šribar A, Šerić M, Antić-Šego G, Božić MA, Prijić A, Lacković T, Peršec J.   +7 more
europepmc   +2 more sources

Tradicionalna upotreba samoniklog jestivog bilja na području općine Kršan (Istra, Hrvatska)

Glasilo Future, 2018
U ovom radu prikazani su rezultati etnobotaničkog istraživanja tradicionalnog korištenja samoniklog jestivog bilja na području općine Kršan, provedenog tijekom 2017. i 2018. godine. Ukupno je dokumentirano 107 biljnih vrsta (od toga 17 kultiviranih vrsta)
Ivana Vitasović-Kosić
exaly   +2 more sources