Results 11 to 20 of about 579 (181)

Involvement of Adenosine A2A Receptors in Anxiety‐Like Behaviors in Tetrahydrocannabinol‐Treated Mice [PDF]

Brain and Behavior, Volume 16, Issue 2, February 2026.
This study evaluated anxiety‐like behavior in mice across treatment and control groups using open field and elevated plus maze tests, followed by hippocampal receptor gene expression analysis. The combined behavioral and molecular data identify potential receptor‐level mechanisms underlying the observed treatment‐associated behavioral changes. ABSTRACT
Burçin Ün, Zeki Akarsakarya, Özlem Yorulmaz Özü, Nermin Seda Ilgaz, Mehmet Bertan Yılmaz, Deniz Seçilmiş, Mehmet Ata Seçilmiş   +6 more
wiley   +2 more sources

Region‐Based Segmentation of Lymph Node Metastases in Whole‐Slide Images of Colorectal Cancer: A Pilot Clinical Study [PDF]

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Digital technologies and artificial intelligence (AI) are transforming medical diagnostics, particularly in pathology. This study presented a two‐stage computer vision model designed to detect colorectal cancer metastases in whole slide images (WSIs) of lymph nodes.
Alexey Fayzullin, Nikita Savelov, Artur Balkivskiy, Elena Ivanova, Anna Timakova, Vladimir Funtikov, Ekaterina Shelomentseva, Nikita Panchenko, Igor Spiridonov, Ivan Korkonishko, Mariia Makhina, Evgeniia Kutuzova, Daur Meretukov, Natalia Kretova, Tatiana Demura, Peter Timashev, Ruslan Parchiev   +16 more
wiley   +2 more sources

Targeting Adenosine A2b Receptor Promotes Penile Rehabilitation of Refractory Erectile Dysfunction [PDF]

Advanced Science, Volume 11, Issue 30, August 14, 2024.
The A2b receptor of adenosine mediates adenosine‐induced penile erection, rather than the A1, A2a, and A3 receptors. Activating the A2b receptor promotes penile rehabilitation of refractory ED by alleviating hypoxia and fibrosis. Dipyridamole, an oral adenosine transporter inhibitor, can promote penile rehabilitation by attenuating hypoxia and fibrosis,
Yang Xiong, Feng Qin, Shanzun Wei, Xingliang Yang, Jun Li, Changjing Wu, Fuxun Zhang, Jiuhong Yuan   +7 more
wiley   +2 more sources

Analytical and Clinical Validation of Solo‐Test Driver: A Targeted Amplicon‐Based NGS Test‐System for FFPE and cfDNA Analysis in Clinical Oncology Setting [PDF]

Journal of Clinical Laboratory Analysis, Volume 39, Issue 6, March 2025.
With the growing demand for compact next‐generation sequencing (NGS) test systems tailored to meet key needs in oncology, the Solo‐test Driver panel serves as a valuable tool for companion diagnostics of solid tumors, demonstrating high reliability, sensitivity, and specificity in line with established guidelines. In this work, we outline the framework
Maxim Ivanov, Alexandra Lebedeva, Ekaterina Belova, Tatiana Grigoreva, Egor Veselovsky, Alexandra Kavun, Anastasiia Taraskina, Olesya Kuznetsova, Vladislav Nikulin, Laima Belyaeva, Daria Kravchuk, Tatyana Lisitsa, Alexey Barinov, Natalia Pospekhova, Saida Aliyarova, Ekaterina Khomenko, Alexey Tryakin, Irina Demidova, Anna Stroganova, Mikhail Fedyanin, Vladislav Mileyko   +20 more
wiley   +2 more sources

Levodopa Dose Equivalency in Parkinson's Disease: Updated Systematic Review and Proposals

Movement Disorders, Volume 38, Issue 7, Page 1236-1252, July 2023., 2023
Abstract Background To compare drug regimens across clinical trials in Parkinson's disease (PD) conversion formulae between antiparkinsonian drugs have been developed. These are reported in relation to levodopa as the benchmark drug in PD pharmacotherapy as ‘levodopa equivalent dose’ (LED).
Stefanie T. Jost, Marie‐Ann Kaldenbach, Angelo Antonini, Pablo Martinez‐Martin, Lars Timmermann, Per Odin, Regina Katzenschlager, Rupam Borgohain, Alfonso Fasano, Fabrizio Stocchi, Nobutaka Hattori, Prashanth Lingappa Kukkle, Mayela Rodríguez‐Violante, Cristian Falup‐Pecurariu, Sebastian Schade, Jan Niklas Petry‐Schmelzer, Vinod Metta, Daniel Weintraub, Guenther Deuschl, Alberto J. Espay, Eng‐King Tan, Roongroj Bhidayasiri, Victor S.C. Fung, Francisco Cardoso, Claudia Trenkwalder, Peter Jenner, K. Ray Chaudhuri, Haidar S. Dafsari, On behalf of the International Parkinson and Movement Disorders Society Non‐Motor Parkinson Disease Study Group   +28 more
wiley   +1 more source

Transferring Jerusalem to Moscow: Maksim Grek’s Letter and Its Afterlife

The Russian Review, Volume 82, Issue 2, Page 248-262, April 2023., 2023
Abstract Few debates in late seventeenth‐century Muscovy were as heated as the controversy over the naming of the Resurrection “New Jerusalem” Monastery (1656). This essay draws attention to an overlooked sixteenth‐century source, a letter by the Greek‐born Slavic translator Maksim Grek (d.
Justin Willson, Ashley Morse
wiley   +1 more source

Characterization and model‐based mechanical analysis of moisture gradients in PA 6

Journal of Applied Polymer Science, Volume 140, Issue 12, March 20, 2023., 2023
Abstract In this contribution, a numerical calculation environment for the determination of the moisture absorption of polyamide 6 (PA 6) is developed. The focus in this context is on modeling and evaluating the influence of locally varying water concentrations and existing moisture gradients on the mechanical properties of the material.
Anna Katharina Sambale, Michael Stanko, Kai Uhlig, Markus Stommel   +3 more
wiley   +1 more source

Production strategies, productivity changes and innovation: An analysis of European turbot aquaculture from 2009 to 2020

Reviews in Aquaculture, Volume 15, Issue 2, Page 610-624, March 2023., 2023
Abstract After more than four decades of production in the European Union, turbot (Psetta maxima) farming is a mature sector with a moderate growth trend (2.74% in 2020). Although up to seven countries started the production of this species, there are only four producing countries in 2020, with more than 90% of the production concentrated in the ...
Raquel Fernández‐González, Marcos I. Pérez‐Pérez, João Correia‐da‐Silva   +2 more
wiley   +1 more source

Didactic game as a means of developing the professionalism of the teacher [PDF]

Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2022
The research raises and reveals the problem of the development of the teachers professionalism. The purpose of the paper is to describe the use, development of didactic games by teachers for students, focused on the development of their individuality ...
Vera M. Zhurakovskaya, Ol'ga A. Olicheva
doaj   +1 more source

Preteklost, ki ne mine?: Nepredelana preteklost v sedanjosti in prihodnosti Istre

Traditiones, 2023
V članku avtorica argumentira, kako je preteklost določa prihodnost, sploh če je preteklost nepredelana, kakor kaže primer slovenskega dela Istre. Primer pravopisne kodifikacije geografskega imena za slovensko Istro pokaže, kako pomembni mejniki iz ...
Katja Hrobat Virloget
doaj   +1 more source