Cognitive and motor performance in Congolese children with konzo during 4 years of follow-up: a longitudinal analysis [PDF]
The Lancet Global Health, 2017 Background: Konzo is an irreversible upper-motor neuron disorder affecting children dependent on bitter cassava for food. The neurocognitive ability of children with konzo over time has yet to be fully documented.
Prof Michael J Boivin, PhD +7 more
doaj +5 more sources
Glutathione peroxidase 3 is a potential biomarker for konzo [PDF]
Nature CommunicationsKonzo is a neglected paralytic neurological disease associated with food (cassava) poisoning that affects the world’s poorest children and women of childbearing ages across regions of sub-Saharan Africa.
Matthew S. Bramble +20 more
doaj +3 more sources
The gut microbiome in konzo [PDF]
Nature Communications, 2021 Here, using metagenomic profiling in 180 individuals from the Democratic Republic of the Congo, the authors find associations between the gut microbiome and konzo, a neurodegenerative disease that mostly affects children and is caused by the consumption ...
Matthew S. Bramble +21 more
doaj +3 more sources
Farmers' perceptions on the causes of cassava root bitterness: A case of konzo-affected Mtwara region, Tanzania. [PDF]
PLoS ONE, 2019 In areas where konzo (a cassava cyanide related paralytic disorder) persists, the agronomic factors causing increased cyanogenic glucoside levels in cassava, during periods without water stress, are hardly known.
Matema L E Imakumbili +4 more
doaj +3 more sources
Soil nutrient adequacy for optimal cassava growth, implications on cyanogenic glucoside production: A case of konzo-affected Mtwara region, Tanzania. [PDF]
PLoS ONE, 2019 Soils in areas affected by konzo (a cassava cyanide intoxication paralytic disorder) are predominantly infertile and probably unable to supply cultivated cassava with the nutrients it needs to achieve optimal growth.
Matema L E Imakumbili +4 more
doaj +3 more sources
Troubles socio-émotionnels de l'enfant en milieu Konzo, un syndrome paralytique de nature épidémique associé à une intoxication cyanhydrique d'origine alimentaire en Afrique sub-saharienne [PDF]
The Pan African Medical Journal, 2018 INTRODUCTION: L'objectif de cette étude était d'élucider le profil socio-émotionnel de l'enfant en milieu Konzo, une paralysie toxico-nutritionnelle sévissant en Afrique sub-saharienne.
Daniel Okitundu Luwa E-Andjafono +7 more
doaj +3 more sources
DNA methylation patterns associated with konzo in Sub-Saharan Africa. [PDF]
Clin Epigenetics, 2022 Konzo, a disease characterized by sudden, irreversible spastic paraparesis, affecting up to 10% of the population in some regions of Sub-Saharan Africa during outbreaks, is strongly associated with dietary exposure to cyanogenic bitter cassava.
Kocher K +6 more
europepmc +2 more sources
When knowledge is not enough: barriers to recommended cassava processing in resource-constrained Kwango, Democratic Republic of Congo [PDF]
Journal of Public Health in Africa, 2023 Background: Despite interventions to provide knowledge and improve bitter cassava processing in the Democratic Republic of Congo (DRC), cassava processing is sub-optimal.
Gisele Bokundabi +7 more
doaj +2 more sources
Research on motor neuron diseases konzo and neurolathyrism: trends from 1990 to 2010. [PDF]
PLoS Neglected Tropical Diseases, 2012 Konzo (caused by consumption of improperly processed cassava, Manihot esculenta) and neurolathyrism (caused by prolonged overconsumption of grass pea, Lathyrus sativus) are two distinct non-infectious upper motor neurone diseases with identical clinical ...
Delphin Diasolua Ngudi +3 more
doaj +5 more sources
Biology, Medicine & Natural Product Chemistry, 2023 Konzo is a neurological disorder of selective upper motor neurons. It is an irreversible paralytic disease associated with prolonged consumption of Cassava.
Lekpa Kingdom David +3 more
doaj +2 more sources