Results 41 to 50 of about 1,823 (200)
Revista Brasileira Militar de Ciências, 2022 O presente estudo objetivou revisar a literatura científica sobre a intoxicação crônica causada por compostos cianogênicos encontrados na mandioca (Manihot esculenta crantz).
Sthéfanny Correia Balduino Silva +1 more
semanticscholar +1 more source
Konzo: from poverty, cassava, and cyanogen intake to toxico-nutritional neurological disease.
PLoS Neglected Tropical Diseases, 2011 Konzo is a distinct neurological entity with selective upper motor neuron damage, characterized by an abrupt onset of an irreversible, non-progressive, and symmetrical spastic para/tetraparesis.
Hipólito Nzwalo, Julie Cliff
doaj +1 more source
International Neuropsychiatric Disease Journal, 2022 Introduction: The present study is aimed at assessing the effect of bitter cassava on blood biochemical parameters of konzo disease induced Wistar rats. Nutritional modification with suphur rich amino acids was used as a measure to correct the impact in ...
Hebinuchi Amadi +2 more
semanticscholar +1 more source
EPRA international journal of multidisciplinary research, 2022 The aim of this study was to assess the anxiety and locomotive activity using elevated plus maze and open field tests in a konzo induced rat model. An experimental research method was used in this study. 20 male Wistar rats were used for this study.
David, L.K, Ibeachu, P.C, Hart, J.S
semanticscholar +1 more source
DNA methylation patterns associated with cyanogenic cassava exposure and konzo in Sub-Saharan Africa
medRxiv, 2021 Konzo, a disease characterized by sudden, irreversible spastic paraparesis, affecting up to 10% of the population in some regions of Sub-Saharan Africa during outbreaks and is strongly associated with dietary exposure to cyanogenic bitter cassava.
K. Kocher +6 more
semanticscholar +1 more source
EFSA Journal, Volume 17, Issue 4, April 2019., 2019 Abstract In 2016, the EFSA Panel on Contaminants in the Food Chain (CONTAM) published a scientific opinion on the acute health risks related to the presence of cyanogenic glycosides (CNGs) in raw apricot kernels in which an acute reference dose (ARfD) of 20 μg/kg body weight (bw) was established for cyanide (CN).
EFSA Panel on Contaminants in the Food Chain (CONTAM) +25 more
wiley +1 more source
Pattern and Epidemiology of Poisoning in the East African Region: A Literature Review
Journal of Toxicology, Volume 2016, Issue 1, 2016., 2016 The establishment and strengthening of poisons centres was identified as a regional priority at the first African regional meeting on the Strategic Approach to International Chemicals Management (SAICM) in June 2006. At this meeting, the possibility of a subregional poisons centre, that is, a centre in one country serving multiple countries, was ...
Dexter Tagwireyi +4 more
wiley +1 more source
, 2021 Konzo is a motor neuron neurodegenerative disease caused by bitter cassava toxicity that presents as a non-progressive spastic paraparesis. The ability of bitter cassava to produce behavioural and structural changes in adult rat nervous system was ...
L. David +3 more
semanticscholar +1 more source
Motor Neuron Diseases in Sub‐Saharan Africa: The Need for More Population‐Based Studies
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 Motor neuron diseases (MNDs) are devastating neurological diseases that are characterised by gradual degeneration and death of motor neurons. Major types of MNDs include amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). These diseases are incurable, with limited disease‐modifying treatment options.
Emmanuel Quansah +2 more
wiley +1 more source
Motor impairments induced by microinjection of linamarin in the dorsal hippocampus of Wistar rats
Neurología (English Edition), 2016 Introduction: Cassava, also known as yuca or manioc (Manihot esculenta Crantz), is a staple food in tropical and subtropical regions since it is an important source of carbohydrates.
E. Rivadeneyra-Domínguez +1 more
doaj +1 more source