Analysis of unmapped regions associated with long deletions in Korean whole genome sequences based on short read data [PDF]
While studies aimed at detecting and analyzing indels or single nucleotide polymorphisms within human genomic sequences have been actively conducted, studies on detecting long insertions/deletions are not easy to orchestrate.
Yuna Lee, Kiejung Park, Insong Koh
doaj +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis [PDF]
Background/Aims To investigate the efficacy and safety of tocilizumab (TCZ) humanized anti-interleukin-6 receptor monoclonal antibody, in Korean patients with active rheumatoid arthritis (RA) refractory to conventional disease modifying anti-rheumatic ...
Han Joo Baek +11 more
doaj +1 more source
Acoustic cues for the korean stop contrast-dialectal variation [PDF]
In this study, cross-dialectal variation in the use of the acoustic cues of VOT and F0 to mark the laryngeal contrast in Korean stops is examined with Chonnam Korean and Seoul Korean.
Choi, Hansook
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Analysis of the relationship between sugar intake and cancer prevalence: a cross-sectional study using the 8th Korea National Health and Nutrition Examination Survey [PDF]
Objectives This study aimed to analyze the association between sugar intake and cancer risk among Korean adults aged 19 years and older. Methods A total of 13,016 adults aged 19 years and older who participated in the 8th Korea National Health and ...
Hye-Ryun Kim, Soo-Kyung Lee
doaj +1 more source
A Syllable-based Technique for Word Embeddings of Korean Words
Word embedding has become a fundamental component to many NLP tasks such as named entity recognition and machine translation. However, popular models that learn such embeddings are unaware of the morphology of words, so it is not directly applicable to ...
Choi, Sanghyuk +3 more
core +1 more source
Overeducation, gender, income and life satisfaction. Panel evidence from Korea [PDF]
One reason often put forward for South Korea’s rapid economic growth has been the rising level of educational attainment of its workforce. Correspondingly, the proportion of Koreans who complete tertiary education has also rapidly increased (and is also ...
Ahmed Lahsen, Amina +2 more
core +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Contemporary cultures and their relationship to adolescent behavior (Korean culture) as a model
Going into any aspect of adolescence is one of the important basics for evaluating society, this is due to the importance of this age stage that determines building the personality of a normal individual and establishing him in a positive way for his ...
Zahra Hadi Kazem
doaj +1 more source

