Results 191 to 200 of about 886,470 (223)

The Kruppel-like Factor (KLF) Family, Diseases, and Physiological Events.

Gene, 2023
The Kruppel-Like Factor family of regulatory proteins, which has 18 members, is transcription factors. This family contains zinc finger proteins, regulates the activation and suppression of transcription, and binds to DNA, RNA, and proteins. Klfs related
Kemal Yuce, Ahmet Ismail Ozkan
semanticscholar   +1 more source

Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish

Science, 2021
Repairing the fish heart Although humans show minimal regenerative capability, zebrafish can regenerate their hearts through a mechanism whereby heart muscle cells (cardiomyocytes) revert to a less mature state and then proliferate to replace the damaged
M. Ogawa   +13 more
semanticscholar   +1 more source

Role of Kruppel-like factor 4 in atherosclerosis.

Clinica chimica acta; international journal of clinical chemistry, 2020
Atherosclerosis is a chronic progressive disease caused by vascular injury, and is induced by the interaction of various inflammatory factors and inflammatory cells.
Chen Yang   +7 more
semanticscholar   +1 more source

Regulation of adipocyte differentiation by clusterin‐mediated Krüppel‐like factor 5 stabilization

The FASEB Journal, 2020
Clusterin (CLU) is a heterodimeric glycoprotein involved in a range of biological processes. We investigated the function of CLU as a novel regulator of adipogenesis. CLU expression increased during 3T3‐L1 preadipocyte differentiation. CLU overexpression
Gyun-Sik Oh   +8 more
semanticscholar   +1 more source

Krüppel-like factor 12 suppresses bladder cancer growth through transcriptionally inhibition of enolase 2.

Gene, 2020
Krüppel-like factors (KLFs) are transcription factors and play important roles in bladder cancer (BC). Clarifying the function of KLFs will provide new strategies for clinical treatment of BC.
Cai Tang, Miao Wang, Yi Dai, Xin Wei
semanticscholar   +1 more source

Kruppel‐like factor 2 disturb non‐small cell lung cancer energy metabolism by inhibited glutamine consumption

The Journal of pharmacy and pharmacology, 2020
Metabolic reprogramming is well accepted as a hallmark of cancer. This study aimed to explore the role of Kruppel‐like factor 2 (KLF2) in aerobic glycolysis and glutamine consumption of energy metabolism in non‐small cell lung cancer (NSCLC) cells.
Song Xiao   +6 more
semanticscholar   +1 more source

EGR1 promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.

Biochimica et Biophysica Acta - Molecular Basis of Disease, 2019
Osteoarthritis is one of the most common orthopedic diseases in elderly people who have lost their mobility. In this study,we observed abnormally high EGR1 expression in the articular cartilage of patients with osteoarthritis. We also found significantly
Xuewu Sun   +9 more
semanticscholar   +1 more source

Dysregulation of Krüppel-like factor 12 in the development of endometrial cancer.

Gynecologic Oncology, 2019
OBJECTIVE Endometrial cancer (EC) remains a malignancy with poor survival outcome. To investigate the role of Krüppel-like factor 12 (KLF12), a transcription factor, in the progression of human EC.
L. Ding   +6 more
semanticscholar   +1 more source

Krüppel-like factor KLF9 inhibits chicken intramuscular preadipocyte differentiation

British Poultry Science, 2019
1. Poultry meat quality is affected by many factors, among which intramuscular fat (IMF) is predominant. IMF content affects tenderness, juiciness and flavour of meat.
Gui-rong Sun   +12 more
semanticscholar   +1 more source

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