Results 181 to 190 of about 205,719 (255)

KRAS Inhibition in Pancreatic Ductal Adenocarcinoma. [PDF]

J Clin Med
Pradeep R, Isbeih NJ, Abraham FF, Noori E, Yeung ZP, Kundranda MN.   +5 more
europepmc   +1 more source

Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C. [PDF]

Nat Commun
Condakes ML, Zhang Z, Danahy DB, Moore RR, Lakkaraju SK, Zhuo X, Amako Y, Borzilleri RM, Balachander SB, Chourb L, Civiello RL, Dongre AR, Downes DP, Drexler DM, Dudiak BM, Dzhekieva L, El-Samin M, Fink BE, Frederick K, Huang C, Khan J, Lees E, Levins CG, McCarthy C, Mintier GA, Mosure K, Parker MF, Powles R, Qi J, Ruzanov M, Sharma S, Sheriff S, Singh AK, Stedman J, Szapiel N, Thompson RL, Vaccaro W, Wang T, Yang T, You D, Meyer MJ, Bronson JJ, Stewart ML.   +42 more
europepmc   +1 more source

KRAS mutation

, 2019
Yuranga Weerakkody, Rohit Sharma, Craig Hacking   +2 more
openaire   +1 more source

The critical role of GRP78/BiP MARylation in ER stress of KRAS-mutant colorectal cancer. [PDF]

JCI Insight
Zhang S, Chen X, Gong Q, Huang J, Tang Y, Xiao M, Li M, Li Q, Wang Y.   +8 more
europepmc   +1 more source

KRAS-dependent glycolytic reprogramming of endothelial cells in sporadic arteriovenous malformations. [PDF]

EMBO Mol Med
Wu R, Khosraviani N, Mansur A, Boudreau E, Largoza GE, Park S, Gustafson D, Raju S, Ching C, Klip A, Wälchli T, Howe KL, Radovanovic I, Wythe JD, Fish JE.   +14 more
europepmc   +1 more source

A new therapeutic approach to <i>KRAS</i> mutant non-small cell lung cancer: the emerging role of exportin 1 inhibition. [PDF]

Transl Lung Cancer Res
von Itzstein MS, Gerber DE.
europepmc   +1 more source

PrP^C-Neutralizing Antibody Confers an Additive Benefit in Combination with 5-Fluorouracil in KRAS-Mutant Colorectal Cancer Models, Associated with Reduced RAS-GTP and AKT/ERK Phosphorylation. [PDF]

Int J Mol Sci
Lee JK, Yoon JY, Lee JY, Lee SH.
europepmc   +1 more source

Phase II Trial of Vemurafenib and Sorafenib Combination in Advanced <i>KRAS</i>-Mutated Metastatic Pancreatic Cancer. [PDF]

J Immunother Precis Oncol
Khawaja MR, Jameson G, Cridebring D, Shannon P, Han H, Moore J, Von Hoff D, Posner RG, Hlavacek WS, Kolch W, Kholodenko BN, Rukhlenko OS, Roe DJ, Wertheim BC, Borazanci E.   +14 more
europepmc   +1 more source

Photodynamic activation of a KRAS RNA G-quadruplex-targeted photosensitizer induces ferroptosis in cisplatin-resistant non-small cell lung cancer. [PDF]

J Biol Chem
Wang XD, Lin JH, Hu MH.
europepmc   +1 more source

Treating Pancreatic Ductal Adenocarcinoma: The Targeted Revolution is Here. [PDF]

Drugs
May MS, Park W, O'Reilly EM.
europepmc   +1 more source