Results 191 to 200 of about 151,900 (300)

Patient-Level KRAS G12C Prevalence among Hispanic/Latino and Non-Hispanic White Patients in Real-world Clinicogenomic Cohorts. [PDF]

Cancer Res Commun
Pilco-Janeta DF, De la Cruz-Puebla M, Guamán-Pilco DR, Montenegro D, Miranda W.   +4 more
europepmc   +1 more source

Identifiable regional and neural network abnormalities in early childhood anxiety

JCPP Advances, EarlyView.
Abstract Background Although the neural underpinnings of anxiety have been investigated, most research has been confined to adolescence and adulthood, with less of a focus on the early childhood period. Little is known about the role of anticipatory fear processing early childhood, which is a sensitive period for anxiety development.
Khalil I. Thompson, Yiwen Zhang, Denny Schaedig, Anna Bankston, Anoushka Parnerkar, Shrinidhi Jeyaram, Nadine Melhem, Susan B. Perlman   +7 more
wiley   +1 more source

Baseline cellular state shapes the molecular impact of mutant Kirsten rat sarcoma viral oncogene homologue (KRAS) alleles in reconstituted pancreatic cancer cells. [PDF]

Mol Omics
Quiñones-Avilés Y, Salovska B, Markham CS, Di Y, Turk BE, Liu Y, Muzumdar MD.   +6 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

KRAS mutations as architects of the tumor immune microenvironment: implications for combination therapies. [PDF]

Front Oncol
Ramachandran V, Koyou HL, Raajasekar S, Mohamed MHB, Inche Mat LNB, Swaminathan V, Salleh MN, Prastiyanto ME, Ahmad NAB.   +8 more
europepmc   +1 more source

Coordinated Immune Activation Following KRAS Inhibition in Syngeneic Models Reveals Molecular Pathways that Potentiate and Limit Antitumor Immunity. [PDF]

Cancer Immunol Res
Lu DR, Osgood T, Ma S, Zhang H, Kanke M, Tan JA, Paudel SN, Zhou H, Estrada J, Yamawaki T, Tarbell K, Rex K, DeVoss J, Martin S, Wang S, Canon J, Lipford JR, Coxon A, Li CM.   +18 more
europepmc   +1 more source

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

CONTROL UNIT FOR VIBRATION SUPPRESSION

, 2018
KRAS, Aleksander Stefan
core   +1 more source

MEK inhibitor-based genomically matched combinatorial targeted therapies in metastatic pancreatic adenocarcinoma with KRAS alterations. [PDF]

Oncologist
Auckley ED, Yohay S, Ying G, Szabo A, Wittmann J, Grahl J, Aldakkak M, Thalji SZ, McFall T, Kurzrock R, George B, Kamgar M.   +11 more
europepmc   +1 more source

Integrating CT‐Based Radiomics Analysis With Serum CEA Level to Predict Neoadjuvant Chemoradiotherapy Response in Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Response to neoadjuvant chemoradiotherapy (NACRT) in locally advanced colorectal cancer (CRC) varies widely, and accurately identifying poor responders is crucial for guiding timely treatment modification. This study aimed to develop an integrated predictive model combining radiomics derived from routine radiotherapy non‐contrast planning ...
Sin‐Hua Moi, Ming‐Yii Huang, Shu‐Han Yang, Chien‐Jang Chen, Ying‐Pei Jhong, Tun‐Wei Hsu, Chien‐Chih Ke   +6 more
wiley   +1 more source