Results 211 to 220 of about 208,301 (303)

A case of T-prolymphocytic leukemia harboring RAS mutation. [PDF]

Ann Hematol
Perrone S, Pacitto G, Tirnetta A, Mulargia C, Angelitti MR, Corbingi A, Ortu La Barbera E, Fabiani E, Voso MT, Di Napoli A.   +9 more
europepmc   +1 more source

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

Increased Risk of Central Mesocolic Lymph Node Metastases in BRAF-Mutated Stage I-III Colon Cancer. [PDF]

J Clin Med
Kuliavas J, Marcinkeviciute K, Vaicekauskaite I, Sabaliauskaite R, Bausys A, Dulskas A, Mickys U, Stulpinas R, Strupas K.   +8 more
europepmc   +1 more source

Comparative Liquid Biopsy Testing for KRAS Mutations From Plasma Cell-Free DNA (cfDNA) and Extracellular Vesicles in Lung Adenocarcinoma. [PDF]

Cancer Rep (Hoboken)
Zahra CJ, Chee TM, Stephens EKH, Keir EJ, Parris BA, O'Farrell HE, Goldsworthy AF, Bowman RV, Yang IA, Fong KM.   +9 more
europepmc   +1 more source

The Earliest Feathers from the Lower Cretaceous Dabeigou Formation of North Hebei: Implications for the Early Evolution of the Jehol Biota

Integrative Zoology, EarlyView.
This study reports two isolated feather fossils from the Lower Cretaceous Dabeigou Formation in northeastern China. Morphological analyses identified them as the earliest known feathered theropods (potentially including avian) in the Jehol Biota. This finding reveals a complex ecosystem at the dawn of the Jehol Biota, bridging the temporal and faunal ...
Qian Wu, Qian‐Nan Zhang, Dang‐Peng Xi   +2 more
wiley   +1 more source

RNA-seq analysis reveals altered gene expression profiles in HMEC-1 cells overexpressing KRAS gene associated with brain arteriovenous malformation. [PDF]

Chin Neurosurg J
Yuan K, Zhao Y, Zhang H, Wang K, Zhou Y, Chen Y, Chen X, Zhao Y, Hao Q.   +8 more
europepmc   +1 more source

KRAS mutation

, 2019
Yuranga Weerakkody, Rohit Sharma, Craig Hacking   +2 more
openaire   +1 more source

Clinical Outcomes of the POPCORN Study: Pharmacodynamics of Pre‐Operative PD1 CheckpOint Blockade and Receptor Activator of NF‐κB Ligand (RANKL) Inhibition in Non‐Small Cell Lung Cancer (NSCLC)—A Phase 1B/2 Trial

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern, Cassie Turner, Rishendran Naidoo, David Godbolt, Amy Ives, Kirsten Popplewell, Zarnie Lwin, Sally Pearson, Kimberley Nelson, Jason Madore, William C Dougall, Brett G. M. Hughes   +11 more
wiley   +1 more source

Prolonged KRAS-MAPK Inhibition Induces Interferon Signaling that Promotes Cell State Transition and Confers Therapeutic Vulnerabilities. [PDF]

Cancer Res
Bulle A, Chen Y, Li H, Chen TH, Khawar IA, Li L, Wang Y, Liu P, Somani VK, Kurupi R, Geng Y, Pereye OB, Bansod S, Le SB, Ruzinova MB, Tran DD, Lim KH.   +16 more
europepmc   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source