Results 111 to 120 of about 2,405 (204)

KRIT1 wt Allele [PDF]

, 2020
openaire   +1 more source

multiple [PDF]

A minimum-labeling approach for reconstructing protein networks ...
Arnon Mazza, Hesso Farhan, Roded Sharan
core  

Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors. [PDF]

ACS Pharmacol Transl Sci, 2023
Francisco KR, Bruystens J, Varricchio C, McCurdy S, Wu J, Lopez-Ramirez MA, Ginsberg M, Caffrey CR, Brancale A, Gingras AR, Hixon MS, Ballatore C.   +11 more
europepmc   +1 more source

Transient Dysphagia as a Presenting Symptom of Familial Cerebral Cavernous Malformation. [PDF]

Cureus
Scott ML, Ross DE.
europepmc   +1 more source

Cerebral cavernous malformation with secondary bacterial infection: illustrative case. [PDF]

J Neurosurg Case Lessons
Gujjari KS, Farsakh A, Mariajoseph FP, Chen BY, Thomas A, Kumar B, Badran A.   +6 more
europepmc   +1 more source

Familial cerebral cavernous malformations caused by a novel germline structural variant in the KRIT1 gene. [PDF]

Neurogenetics
Pilz RA, Begemann M, Pfister S, Boonsawat P, Rauch A, Kurth I, Felbor U, Rath M.   +7 more
europepmc   +1 more source

ROLE OF KRIT1 IN THE ACQUISITION OF AGGRESSIVE PHENOTYPE IN CANCER CELLS

K-Rev Interaction Trapped protein-1 (KRIT1) is a scaffold protein known to form functional protein complexes involved in physiologically important signaling networks. While it is primarily recognised for its association with Cerebral Cavernous Malformations (CCMs), KRIT1 also plays critical roles in tumor formation and the acquisition of malignant ...
openaire   +1 more source

Flow-Sensitive HEG1 Controls eNOS Activity to Prevent Endothelial Dysfunction, Hypertension, and Atherosclerosis. [PDF]

Arterioscler Thromb Vasc Biol
Clark MD, Kim Y, Romero CA, Kang DW, Baek KI, Song EJ, Kellum CE, Bowman-Kirigin JA, Park C, Hung RC, Choi L, Kapoor V, Tsuji S, Pollock JS, Jo H.   +14 more
europepmc   +1 more source

Novel insights into the relationship between KRIT1 and ROS homeostasis: KRIT1 loss-of-function causes a ROS-dependent upregulation of transcription factors involved in oxidative stress response

, 2012
Loss-of-function mutations of the KRIT1 gene (CCM1) have been associated with the pathogenesis of Cerebral Cavernous Malformations (CCM), a major cerebrovascular disease characterized by abnormally enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, and fatal intracerebral haemorrhage.
GOITRE, Luca, Braggion S., Cutano V., Trapani E., Morina A., Canzoneri R., PERGOLIZZI, Barbara, BIASI, Fiorella, Ferro E, Trabalzini L., RETTA, Saverio Francesco   +10 more
openaire   +2 more sources

Clinical and molecular landscape of paediatric cerebral and spinal cavernous malformations. [PDF]

Brain Commun
Benichi S, Balducci E, Benzakoun J, Ghannam B, Attieh C, Metais A, Bourgeois M, Guida L, Kaltenbach S, Tauziede-Espariat A, Riant F, Villarese P, Lefevre C, Roux CJ, Puget S, Naggara O, Oppenheim C, Nabbout R, Boddaert N, Beccaria K, Tournier-Lasserve E, Kossorotoff M, Varlet P, Asnafi V, Canaud G, Blauwblomme T.   +25 more
europepmc   +1 more source