Results 81 to 90 of about 41,533 (292)
Advanced Science, EarlyView.We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang +9 more
wiley +1 more source
Low transverse emittance electron bunches from two-color laser-ionization injection [PDF]
, 2013 A method is proposed to generate low emittance electron bunches from two color laser pulses in a laser-plasma accelerator. A two-region gas structure is used, containing a short region of a high-Z gas (e.g., krypton) for ionization injection, followed by
Benedetti, Carlo +9 more
core +1 more source
Advanced Science, EarlyView.AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li +6 more
wiley +1 more source
Advanced laboratory for testing plasma thrusters and Hall thruster measurement campaign
Nukleonika, 2016 Plasma engines are used for space propulsion as an alternative to chemical thrusters. Due to the high exhaust velocity of the propellant, they are more efficient for long-distance interplanetary space missions than their conventional counterparts.
Szelecka Agnieszka
doaj +1 more source
REALIZING THE GREAT NATION THROUGH CULTURAL LITERACY [PDF]
, 2015 Mastery of literacy in all aspects of life become the backbone of the progress of civilization of a nation. It is impossible to become a great nation, if only relying on oral culture in the institutions of learning coloring school.
Setyawati, Rukni
core
Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics
Advanced Science, EarlyView.Deformation‐driven suction cups enable robust, reversible adhesion of wearable electronics to human skin spanning wide mechanical compliance, without adhesives or tight straps. By integrating mechanics modeling, experiments, and contact mechanics theory, this work reveals how cup geometry, substrate compliance, and interfacial adhesion govern suction ...
Seola Lee +10 more
wiley +1 more source
Extended Fused Carbazole‐BODIPY, High Brightness NIR Organic Dyes
Angewandte Chemie, EarlyView.Highly fused boron‐dipyrromethene (BODIPY) with a strong donor group has been synthesized, and their photophysical behaviors fully characterized. They exhibit outstanding brightness for fluorophores emitting in the NIR region. Water‐soluble nanoparticles filled with one of these dyes demonstrate high efficiency as the NIR II visualization agent ...
Fabien Ceugniet +9 more
wiley +2 more sources
IMPACTS OF SOCIAL MEDIA TOWARDS LANGUAGE SHIFT AMONG UNIVERSITY STUDENTS [PDF]
, 2015 Social Media Applications are inevitable in today’s people’s lives, especially for university students who cannot be separated with their gadgets. It is undeniable that the use of social media changes the way people communicate with each other, from ...
Karjo, Clara Herlina
core
Cationic mRNA Lipid Nanoparticles for Ex Vivo NanoCAR‐T Cell Engineering
Advanced Science, EarlyView.This study compares charge‑neutral and cationic lipidnanoparticles (LNPs) for ex vivo mRNA delivery to T cells, revealing distinctdependencies on medium composition and T cell activation. Where conventional LNPs benefit from ApoE‐dependent T cell targeting, cationic DOTAP‑modified LNPs mediate unspecific charge‑dependent transfection.
Laure Harinck +9 more
wiley +1 more source
Angewandte Chemie, EarlyView.Integrated structural analysis of N. vulgaris formate dehydrogenase AB, an enzyme with applications in climate change mitigation, is reported. The substrate/product diffusion pathways were fully mapped, and a retention site was identified that transiently holds substrates and has a key role in CO2‐reducing activity.
Guilherme Vilela‐Alves +8 more
wiley +2 more sources