The natural polyphenol fortunellin and its structural analogs are inhibitors of the SARS-CoV-2 main proteinase dimerization, as revealed by molecular simulation studies [PDF]
arXiv, 2020 3CL-Pro (or M-Pro) is the SARS-CoV-2 main protease, acting as a homodimer, is responsible for the cleavage of the large polyprotein 1ab transcript in proteins acting on viral growth and replication. 3CL-Pro has been one of the most studied SARS-CoV-2 proteins and the subject of therapeutic interventions, targeting its catalytic domain. A number of drug
arxiv
Virtual screening and molecular dynamics simulation study of plant protease inhibitors against SARS-CoV-2 envelope protein. [PDF]
Inform Med Unlocked, 2022 Kirar M, Singh H, Sehrawat N.
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Insulin-Loaded Soybean Trypsin Inhibitor-Chitosan Nanoparticles: Preparation, Characterization, and Protective Effect Evaluation. [PDF]
Polymers (Basel), 2023 Zhang Y +5 more
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Plant-Derived Compounds and Extracts as Modulators of Plasmin Activity-A Review. [PDF]
Molecules, 2023 Kolodziejczyk-Czepas J, Czepas J.
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Studies of enzyme inhibitors and endochitinase in seeds of job’s tears (Coix lachryna-jobi) [PDF]
, 1994 Studies of the purification, characterization and primary structure of protein inhibitors of trypsin and -amylase from seeds of Job's Tears (Coix lachryma-jobi) were undertaken.
Ary, Marta Baccache
core
Plant Kunitz Inhibitors and Their Interaction with Proteases: Current and Potential Pharmacological Targets. [PDF]
Int J Mol Sci, 2022 Bonturi CR +7 more
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Interactions between Soybean Trypsin Inhibitor and Chitosan in an Aqueous Solution. [PDF]
Polymers (Basel), 2023 Zhang Y, Liu R, Li H, Li Y, Liu X.
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Extração e purificação de inibidores proteolíticos em sementes de leguminosas arbóreas da Amazônia [PDF]
, 2009 A família Fabaceae é importante na indústria madeireira, como fonte de proteínas vegetais e contém uma grande variedade de biomoléculas com potencial para aplicação industrial, incluindo os inibidores proteolíticos, os quais são proteínas que podem atuar
Chevreuil, Larissa Ramos
core
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species. [PDF]
Cell Death Discov, 2023 Schiavi A +13 more
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Pollination in Nicotiana alata stimulates synthesis and transfer to the stigmatic surface of NaStEP, a vacuolar Kunitz proteinase inhibitor homologue [PDF]
After landing on a wet stigma, pollen grains hydrate and germination generally occurs. However, there is no certainty of the pollen tube growth through the style to reach the ovary. The pistil is a gatekeeper that evolved in many species to recognize and
Busot, Grethel Yanet +5 more
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