A novel Kupffer cell-targeting nanoparticle system to Mitigate alcohol-associated liver disease. [PDF]
Unagolla JM +7 more
europepmc +1 more source
Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections. [PDF]
Hirako IC +8 more
europepmc +1 more source
Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu +8 more
wiley +1 more source
SLC16A3 as an immunosuppressive Kupffer cell marker predicts poor prognosis in HBV-positive hepatocellular carcinoma. [PDF]
Zhang J +7 more
europepmc +1 more source
Increased hepatic PAFR expression in MASLD is associated with histological disease severity and may contribute to progression through platelet activation, whereas circulating Lp‐PLA2 levels lack discriminatory value as a noninvasive biomarker. ABSTRACT Objective This study aimed to investigate the platelet‐activating factor (PAF) pathway in obesity ...
Joan Duran‐Bertran +11 more
wiley +1 more source
Viral-Directed Augmentation of Kupffer Cell Cross-Presentation Provokes Antitumor Immunity Against Liver Metastasis. [PDF]
Chen C +8 more
europepmc +1 more source
Identification of the mouse Kupffer cell receptors recognizing pneumococcal capsules by affinity screening. [PDF]
An H, Tian X, Huang Y, Zhang JR.
europepmc +1 more source
openaire +1 more source
Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi +12 more
wiley +1 more source
Divergent Hepatic and Adipose Tissue Effects of Kupffer Cell Depletion in a Male Rat Model of Metabolic-Associated Steatohepatitis. [PDF]
Wiszniewski M +5 more
europepmc +1 more source

