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Carbon monoxide-loaded red blood cells ameliorate metabolic dysfunction-associated steatohepatitis progression via enhancing AMP-activated protein kinase activity and inhibiting Kupffer cell activation. [PDF]

Redox Biol
Yanagisawa H, Maeda H, Noguchi I, Tanaka M, Wada N, Nagasaki T, Kobayashi K, Kanazawa G, Taguchi K, Chuang VTG, Sakai H, Nakashima H, Kinoshita M, Kitagishi H, Iwakiri Y, Sasaki Y, Tanaka Y, Otagiri M, Watanabe H, Maruyama T.   +19 more
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Amphibia Kupffer cells

Microscopy Research and Technique, 2002
AbstractAmphibia Kupffer cells (i.e., liver resident macrophages) show many common characteristics when compared with Mammalia Kupffer cells: filopodia, microvillous‐like structures, lamellipodia, fuzzy coat, coated vesicles, bristled vacuoles, nonspecific esterase activity, and pinocytotic and phagocytic activity are present both in Amphibia and ...
SICHEL G, SCALIA, Marina, C. CORSARO
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Kupffer Cells in the Liver

Comprehensive Physiology, 2013
Abstract Kupffer cells are a critical component of the mononuclear phagocytic system and are central to both the hepatic and systemic response to pathogens. Kupffer cells are reemerging as critical mediators of both liver injury and repair.
Laura J, Dixon, Mark, Barnes, Hui, Tang, Michele T, Pritchard, Laura E, Nagy   +4 more
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Kupffer Cells in Hepatocellular Adenomas

The American Journal of Surgical Pathology, 1987
Hepatocellular adenomas are usually visualized as defects on technetium-99m-sulfur colloid liver scans, a fact which has been attributed to the absence of phagocytic Kupffer cells in the tumors. To determine whether this is true, seven hepatocellular adenomas were subjected to immunoperoxidase staining for lysozyme, a marker of mononuclear phagocytes ...
Z D, Goodman, U V, Mikel, P R, Lubbers, P R, Ros, J M, Langloss, K G, Ishak   +5 more
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Differentiation and function of Kupffer cells

Medical Electron Microscopy, 2004
Kupffer cells are the largest population of tissue macrophages. They are predominantly distributed in the lumen of hepatic sinusoids and exhibit endocytic activity against blood-borne materials entering the liver. Macrophage colony-stimulating factor and other growth factors regulate Kupffer cell differentiation in the fetal and adult period.
Makoto, Naito, Go, Hasegawa, Yusuke, Ebe, Takashi, Yamamoto   +3 more
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TNF receptors in Kupffer cells

Journal of Receptors and Signal Transduction, 2011
Somatostatin is a mediator of immune functions and has been used as an antineoplastic agent in animal models and human neoplasias. We have demonstrated that Octreotide inhibits only LPS induced secretion of proinflammatory cytokines including TNFa by Kupffer cells (KC).
Maria, Georgiadou, George, Notas, Costas, Xidakis, Ioannis, Drygiannakis, Ourania, Sfakianaki, Stefanos, Klironomos, Vassilis, Valatas, Elias, Kouroumalis   +7 more
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Isolation of Liver Kupffer Cells

Current Protocols in Toxicology, 2002
AbstractIsolation of Liver Kupffer Cells (Matthias Froh, Akira Konno, Ronald G. Thurman, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina). Kupffer cells, the resident macrophages of the liver, play a major role in the pathogenesis of several diseases.
Matthias, Froh, Akira, Konno, Ronald G, Thurman   +2 more
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Melanosynthesis in the kupffer cells of amphibia

Comparative Biochemistry and Physiology Part A: Physiology, 1982
Abstract 1. 1. Radioactive melanins have been isolated from liver sections of Rama esculenta L. after incubation in survival with either [ 14 C]tyrosine or [ 14 C]DOPA. 2. 2. In both cases incorporation values are at least two fold when compared with inactivated controls. 3. 3.
CICERO, ROSINA GIUSEPPA, SCIUTO S., CHILLEMI R., SICHEL G.   +3 more
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Kupffer Cell mRNA Sequencing

2020
The liver is an important organ for the regulation of whole-body metabolism, as well as for immunity. Kupffer cells (KCs) are specialized liver-resident macrophages and the major population of immune cells in the liver. These cells have been shown to play an important role for the regulation of liver homeostasis, and many studies have thus linked these
Emelie, Barreby, Connie, Xu
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