Results 91 to 100 of about 245,162 (297)

Carbon market and climate negotiations. [PDF]

open access: yes
In the wake of the Copenhagen Conference and the outstanding issue of shaping climate change mitigation for the period beyond that covered by the Kyoto protocol, this paper puts into context the various economic instruments available fot tackling climate
De Perthuis, Christian, Shaw, Suzanne
core  

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai   +15 more
wiley   +1 more source

Compliance and Imperfect Intertemporal Carbon Trading [PDF]

open access: yes
This paper examines three compliance mechanisms of the Kyoto Protocol: (i) the restoration rate, (ii) the commitment period reserve rule, and (iii) the suspension mechanism, all potentially constraining greenhouse gas emissions trading across time and ...
Godal, Odd, Klaassen, Ger
core  

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

open access: yesAdvanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li   +5 more
wiley   +1 more source

Transparency and Kyoto Protocol: reply to Mollicone and Federici

open access: yesForest@, 2007
A reply to the letter by Mollicone and Federici, published in the current issue of this journal, and a restatement of the transparent objectives and expected results from the CarboItaly project.
Gianelle D   +11 more
doaj  

The Economics of "When" Flexibility in the Design of Greenhouse Gas Abatement Policies [PDF]

open access: yes
This paper focuses on the economic desirability of the fixed and relatively short-term greenhouse gas targets and timetables in the Kyoto Protocol. The Protocol provides flexibility in which greenhouse gases to control, where control can be implemented ...
Anderson, John   +2 more
core  

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Estimating the effects of Kyoto on bilateraltrade flows using matching econometrics [PDF]

open access: yes
Many Kyoto countries fear a loss of competitiveness due to unilateral climate policyefforts; policymakers therefore call for carbon-related border tax adjustments.
Gabriel J. Felbermayr, Rahel Aichele
core  

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Comparing Permit Allocation Options: The Main Points [PDF]

open access: yes
In discussions about the policy design of domestic emission trading, e.g., when implementing the Kyoto Protocol, the two permit allocation alternatives ­ auctioning and allocation gratis (grandfathering) ­ are often pitted against each other as ...
Bohm, Peter
core  

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