Results 71 to 80 of about 334,489 (293)

Articulating a Notion of Self-as-Mediation—Grounded from Science and Art Towards the Religious

Religions
The intention of this paper is to develop an original notion of self-as-mediation, where a reimagining of the function of art as a phenomenological/epistemological praxis will be the methodological vehicle. The argument here will unfold over four moments.
Lauren Ana Walker
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IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

Safety in Japanese Advanced Breast Cancer Patients Who Received Abemaciclib in MONARCH 2 and MONARCH 3: Assessment of Treatment-Emergent Neutropenia, Diarrhea, and Increased Alanine Aminotransferase and Aspartate Aminotransferase Levels

Cancer Management and Research, 2022
Norikazu Masuda,1 Yucherng Chen,2 Tsutomu Kawaguchi,3 Koji Dozono,4 Masakazu Toi5 1Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan; 2Safety Science, Quality and Patient Safety, Eli Lilly Japan K.K.,
Masuda N, Chen Y, Kawaguchi T, Dozono K, Toi M   +4 more
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The Dynamical Correlation Function of the XXZ Model

, 1994
We perform a spectral decomposition of the dynamical correlation function of the spin $1/2$ XXZ model into an infinite sum of products of form factors. Beneath the four-particle threshold in momentum space the only non-zero contributions to this sum are ...
Bougourzi, A. H., Weston, Robert A.
core   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Decreased white matter integrity before the onset of delusions in patients with Alzheimer's disease: diffusion tensor imaging

Neuropsychiatric Disease and Treatment, 2012
Shutaro Nakaaki,1 Junko Sato,2 Katsuyoshi Torii,2 Mizuki Oka,1 Atsushi Negi,2 Takashi Nakamae,3 Jin Narumoto,3 Jun Miyata,4 Toshi A Furukawa,5 Masaru Mimura11Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan; 2Department of ...
Nakaaki S, Sato J, Torii K, Oka M, Negi A, Nakamae T, Narumoto J, Miyata J, Furukawa TA, Mimura M   +9 more
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RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Influence of Trabeculectomy with Mitomycin C on Longitudinal Changes in the Visual Field in Glaucoma Patients with High Myopia

Clinical Ophthalmology, 2023
Yutaro Yamagata,1 Kenji Suda,1 Tadamichi Akagi,1,2 Hanako Ohashi Ikeda,1 Takanori Kameda,1 Tomoko Hasegawa,1 Masahiro Miyake,1 Akitaka Tsujikawa1 1Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan;
Yamagata Y, Suda K, Akagi T, Ikeda HO, Kameda T, Hasegawa T, Miyake M, Tsujikawa A   +7 more
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A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Clinical outcomes after initial treatment of methicillin-resistant Staphylococcus aureus infections

Infection and Drug Resistance, 2018
Nobuaki Shime,1,2 Nobuyuki Saito,3 Miya Bokui,4 Naoki Sakane,5 Mitsuhiro Kamimura,6 Tsutomu Shinohara,7 Tadashi Kosaka,8 Hisashi Ishikura,9 Atsuko Kobayashi,10 1Department of Emergency and Critical Care Medicine, Graduate School of Biomedical & ...
Shime N, Saito N, Bokui M, Sakane N, Kamimura M, Shinohara T, Kosaka T, Ishikura H, Kobayashi A   +8 more
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