Results 71 to 80 of about 939,728 (251)

El láser: una contundente arma de guerra o un afilado bisturí [PDF]

, 1983
José Antonio Martín Pereda, vicerrector de Investigación de la Universidad Politécnica de Madrid en 1983, nos cuenta cómo en 1957 el norteamericano Townes y los soviéticos Basov y Prokorov desarrollaron, al mismo tiempo, el primer máser, apareciendo ...
Martín Pereda, José Antonio
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Caracterización “in-situ” de aerosoles en entornos industriales agresivos mediante libs a distancia [PDF]

, 2018
Este trabajo se ha centrado en evaluar las posibilidades analíticas de detección “in situ” de aerosoles sólidos generados durante la fabricación de acero, así como en la determinación de su composición elemental, Con este objetivo, se diseñó un ...
Cabalin-Robles, Luisa Maria, Delgado Pérez, Tomás, Girón, David, Laserna-Vázquez, José Javier, Ruiz-del-Castillo, Javier   +4 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Sorting, shredding and smelting scrap

Valuation Studies, 2020
The global economy of e-waste recycling has received much attention in recent waste studies literature. This article gives an account from the inside of two different sites within a leading high-tech recycling and smelting company in which such e-waste ...
Stefan Laser
doaj   +1 more source

Microconformado de Materiales Metálicos mediante Pulsos Láser en el Dominio de ns [PDF]

, 2008
La demanda de miniaturización introducida, entre otros, por la industria de fabricación de MEMS (Micro Electro Mechanical Systems), hace necesario caracterizar y validar los procesos que emplean el láser en el microconformado de materiales metálicos a ...
Garcia Garcia, Oscar, García-Ballesteros Ramírez, Juan José, Molpeceres Álvarez, Carlos Luis, Morales Furió, Miguel, Ocaña Moreno, José Luis, Porro González, Juan Antonio, Sanchez Perez, Angel M.   +6 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

CAVIDAD RESONANTE CILÍNDRICA DE SECCIÓN ELÍPTICA PARA EL ANÁLISIS DE SEÑALES OPTOACÚTICAS

Anales (Asociación Física Argentina), 2005
Se propone una cavidad resonante de sección transversal elíptica para la generación de señales optoacústicas en una cavidad cilíndrica. Se analizan los posibles modos de vibración a ser excitados en función de la excentricidad de la elipse de la sección,
J. L. Ladaga, C. F. Mosquera
doaj  

Towards a digital model of zebrafish embryogenesis. Integration of Cell Tracking and Gene Expression Quantification [PDF]

, 2010
We elaborate on a general framework composed of a set of computational tools to accurately quantificate cellular position and gene expression levels throughout early zebrafish embryogenesis captured over a time-lapse series of in vivo 3D images.
Bourgine, Paul, Castro González, Carlos, Desnoulez, Sophie, Douloquin, Louise, Ledesma Carbayo, María Jesús, Luengo Oroz, Miguel Ángel, Melani, Camilo, Peyrieras, Nadine, Santos Lleo, Andres de, Savy, Thierry   +9 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source