Results 61 to 70 of about 1,938,810 (208)

Effects of picosecond laser on the multi-colored tattoo removal using Hartley guinea pig: A preliminary study. [PDF]

PLoS ONE, 2018
Picosecond lasers have emerged as the leading technology for tattoo removal due to their shorter pulse lengths. To clarify the features of picosecond lasers, we compared picosecond and nanosecond lasers in their ability to remove multi-colored tattoo in ...
Mi Soo Choi, Hee Seok Seo, Jong Gu Kim, Sung Jay Choe, Byung Cheol Park, Myung Hwa Kim, Seung Phil Hong   +6 more
doaj   +1 more source

Complex lasers with controllable coherence [PDF]

Nature Reviews Physics, 2018
Lasers have enabled scientific and technological progress, owing to their high brightness and high coherence. However, the high spatial coherence of laser illumination is not always desirable, because it can cause adverse artefacts such as speckle noise.
Hui Cao, R. Chriki, S. Bittner, A. Friesem, N. Davidson   +4 more
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Ultralow threshold surface emitting ultraviolet lasers with semiconductor nanowires

Scientific Reports, 2023
Surface-emitting (SE) semiconductor lasers have changed our everyday life in various ways such as communication and sensing. Expanding the operation wavelength of SE semiconductor lasers to shorter ultraviolet (UV) wavelength range further broadens the ...
Mohammad Fazel Vafadar, Songrui Zhao
doaj   +1 more source

Advances in All-Solid-State Passively Q-Switched Lasers Based on Cr⁴⁺:YAG Saturable Absorber

Photonics, 2021
All-solid-state passively Q-switched lasers have advantages that include simple structure, high peak power, and short sub-nanosecond pulse width. Potentially, these lasers can be applied in multiple settings, such as in miniature light sources, laser ...
Jingling Tang, Zhenxu Bai, Duo Zhang, Yaoyao Qi, Jie Ding, Yulei Wang, Zhiwei Lu   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Optomechanical Cavities Based on Epitaxial GaP on Nominally (001)-Oriented Si [PDF]

Gallium Phosphide (GaP) has recently received considerable attention as a suitable material for building photonic integrated circuits due to its remarkable optical and piezoelectric properties.
Mercadé, Laura, Griol Barres, Amadeu, Mouriño, Paula, García Carretero, Basilio Javier, Griol, Amadeu, Fernández Garrido, Sergio, García, Basilio Javier, Resta-López, Raquel, Martínez, Alejandro, Sinusía Lozano, Miguel, Resta, Raquel, Fernández-Garrido, Sergio, Gómez, Víctor J., Ben Saddik, Karim, Gómez-Hernández, Víctor Jesús, Sinusia-Lozano, Miguel, Barrigón, Enrique, Mouriño-Miñambres, Paula   +17 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source