Results 31 to 40 of about 1,186,422 (232)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Carcinome in situ conjonctival: une lésion rare à ne pas méconnaitre
The Pan African Medical Journal, 2017 Un homme âgé de 30 ans sans antécédents pathologiques notables, avait consulté pour l'apparition trois mois auparavant d'une lésion cornéenne de l'éil droit.
Rim Limaiem, Faten Limaiem
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Vive les mathématiques : le faux aléa, chassé par la lésion
, 1992 International audienceVente.
Gautier, Pierre-Yves
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Alchornea yambuyaensis, plante toxique pour le bétail au Congo belge
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1954 Aucun résumé disponible.
M. Hidiroglou
doaj +1 more source
Lésion cutanée inhabituelle révelatrice d´une leucémie aigue lymphoblastique de phénotype T
PAMJ Clinical Medicine, 2020 La leucémie aigue lymphoblastique (LAL) est une hémopathie maligne rare. Sa prise en charge a connu une véritable révolution au cours des vingt dernières années. Nous rapportons l´observation d´un patient âgé de 65 ans, admis pour syndrome d´insuffisance
Nouama Bouanani, Mounia Bendari
doaj +1 more source
FEBS Letters, EarlyView.Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley +1 more source