Results 51 to 60 of about 100,068 (246)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Pyoderma gangrénosum végétant idiopathique

The Pan African Medical Journal, 2014
Le pyoderma gangrenosum est une dermatose inflammatoire rare faisant partie des dermatoses neutrophiliques évoluant vers des ulcères douloureux; trainants d'évolution torpide; on distingue la forme ulcéreuse; pustuleuse; bulleuse et la forme ...
Karima Chakir, Badreddine Hassam
doaj   +1 more source

"Tu vaudras aux yeux des autres ce que tu seras à te yeux": travail de Bachelor [PDF]

, 2017
Actuellement, la société porte une attention particulière à l’image corporelle. Or les personnes vivant avec une paraplégie présentent une image du corps qui n’entre pas dans les “normes” sociétales.
Bourson, Bénédicte, Cofré Mendes, Cristel, Irakoze, Nelly   +2 more
core  

Toward a human neuropsychology of emotional behavior? [PDF]

, 1979
peer ...
Seron, Xavier, Van der Linden, Martial
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Current Prevalence of Tuberculous Lesions among Slaughtered Cattle in Northeastern States of Nigeria

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2009
An abattoir study on the prevalence of bovine tuberculosis in six cattle-producing states of Nigeria was carried out from 2000 to 2004. Out of 302,700 slaughtered head of cattle examined postmortem, 4.05% (CI: 3.12, 4.98) had tuberculosis lesions.
M. M. Aliyu, J. Y. Adamu, Y. A. Bilyaminu   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Premiers cas authentiques de farcin du boeuf en Afrique Occidentale Française

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1958
Aucun résumé disponible en français.
Georges Mémery, P. Mornet, A. Camara
doaj   +1 more source

Traitement endovasculaire des artères jambières pour ischémie critique : Travail d'analyse du suivi d'une cohorte de patients [PDF]

, 2015
Introduction Le traitement endovasculaire s'est progressivement imposé comme le traitement de premier choix de l'ischémie critique (IC) des membres inférieurs en raison de l'amélioration du matériel et des bons résultats en terme de morbi-mortalité ...
VANOLI, S.
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source