Results 101 to 110 of about 234,030 (235)

Lúpus eritematoso sistêmico a gestação e os Rins

, 2016
O Lúpus Eritematoso Sistêmico é uma doença crônica multifatorial de etiopatogenia desconhecida, que atinge principalmente mulheres negras em idade reprodutiva, entre 15 e 45 anos, podendo causar complicações renais e durante a gestação. O presente estudo
dos Reis Severiano, Dryelle Lohanne, Costa Carneiro, Cristiene, Sena Passos, Xisto   +2 more
core  

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source

Lupus Panniculitis Presenting as Multiple Discharging Sinuses

Clinical Dermatology Review
Lupus erythematosus profundus (lupus panniculitis) is an uncommon variant of panniculitis, which may present as localized entity or in association with systemic lupus erythematosus or discoid lupus erythematosus.
Kanathur Shilpa, Eswari Loganathan, HN Mohan   +2 more
doaj   +1 more source

Diagnóstico e tratamento de lúpus eritematoso discoide canino: Relato de caso

, 2018
O complexo Lúpus Eritematoso (LE) é constituído por um conjunto de dermatopatias autoimunes que pode se manifestar em duas apresentações clinicas principais: o Lúpus Eritematoso Sistêmico (LES) e o Lúpus Eritematoso Discóide (LED).
Michelle Costa e Silva, Euclides R Pereira Junior, Lorena Vasconcelos de Lucena, Cynthia Levi Baratta Monteiro, Vanessa Lucas da Silva, Raimundo Diones Carneiro   +5 more
core   +1 more source

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

Advanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao, Xinyun Zhang, Qian Ren, Xue Song, Meifang Zhao, Rongshen Wang, Haocheng Du, Yan Chen, Peigen Xu, Jiangyun Liu, Jian Zhang, Jingjing Ma   +11 more
wiley   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Lesão palpebral como manifestação primária do lúpus eritematoso discóide

, 2013
O lúpus eritematoso discóide é uma desordem autoimune que geralmente afeta áreas da pele expostas ao sol. A apresentação de lesões palpebrais na ausência de outras anormalidades cutâneas é incomum, sendo o envolvimento da pálpebra inferior prevalente em ...
Juliana Grilo Teles, Patricia Picciarelli de Lima, Suzana Matayoshi, Davi Araf, Juliana Mika Kato   +4 more
core   +1 more source

The Novel Viral Non‐Coding RNA LMP2A‐IT1 Promotes the Lytic Replication of EBV

Advanced Science, EarlyView.
Decades after its discovery, EBV's genome still harbours unannotated “dark matter”. LMP2A‐IT1, a novel EBV‐encoded transcript identified in this work, is strongly upregulated during lytic replication and promotes BZLF1 expression, likely through activation of inflammatory responses, thereby enhancing viral propagation in a self‐reinforcing positive ...
Zheng‐Zhou Lu, Jun‐Fei Wu, Nannan Zhu, Ming‐Hui Yang, Le‐Le Zhang, Yuan‐Tao Liu, Wei‐Jun Chen, Jin‐Kun Tang, Jia‐Wei Ge, Chao‐Bo Lei, Tao Zhang, Yu Wang, Chao‐Yun Huang, Qian Zhong, Mu‐Sheng Zeng, Yan Li   +15 more
wiley   +1 more source

Eventos arrítmicos no lúpus eritematoso sistêmico

Revista Brasileira de Reumatologia
Mais da metade dos pacientes com lúpus eritematoso sistêmico (LES) apresentam envolvimento cardíaco. Porém, não existem estudos de prevalência de eventos arrítmicos (EA) nesta doença, nem de correlações laboratoriais preditoras de sua ocorrência.
Ricardo Alkmim Teixeira, Eduardo Ferreira Borba, Eloisa Bonfá, Martino Martinelli Filho   +3 more
doaj  

Considerações sobre lúpus eritematoso sistêmico

, 2013
Lupus is a rare autoimmune disease characterized by formation of the auto-antibodies which act against the body's own tissues. The patient produces harmful substances to your body and the antibody, which is a defense mechanism, becomes a mechanism of ...
Carneiro, Ana Cláudia Álvares [UNESP]
core   +1 more source