Results 141 to 150 of about 61,859 (243)

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

open access: yesChemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley   +4 more
wiley   +1 more source

Method for phenotypic identification of Acinetobacter seifertii bacteria

open access: yesИнфекция и иммунитет
. The aim of the study is to increase the accuracy of Acinetobacter seifertii species identification by the phenotypic method. Study objects: 5 strains of A.
E. P. Sivolodskii   +2 more
doaj   +1 more source

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil   +6 more
wiley   +1 more source

16S rRNA based identification of _Aeromonas sp. kumar_ by constructing phylogenetic tree and identification of regulatory elements from the harmful Red Tide bloom, Gulf of Mannar [PDF]

open access: yes, 2009
A bacterial strain, designated _Aeromonas sp. kumar_, was isolated from a water sample collected from Red tide Bloom occurred in the region of Gulf of Mannar region, Puthumadam Coast, India and the strain was identified using 16S rRNA based ...
A. K. Kumaraguru   +2 more
core   +1 more source

Extraction, Structural Characterization and Anti‐Inflammatory Activity of Polysaccharides From Conioselinum vaginatum

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
This study employed an ultrasonic‐assisted extraction (UAE) method combined with column chromatography purification to obtain two homogeneous polysaccharides (CVP‐I and CVP‐II) from Conioselinum vaginatum, which exhibited distinct physicochemical properties and structural characteristics, and exerted anti‐inflammatory effects by inhibiting the ...
Conghui Ren   +6 more
wiley   +1 more source

Laboratory Analysis of Fecal Lactobacillus Strains and pH in Tobacco Smokers: A Comparative Study From a Developing Country

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Tobacco smoking is a major cause of preventable mortality globally, disproportionately impacting developing countries. While its systemic health effects are well‐known, the influence of tobacco on gut microbiota—especially beneficial Lactobacillus species—remains poorly explored in resource‐limited settings.
Afshin Shabibi   +4 more
wiley   +1 more source

Structural Features of Highly Bioactive Citrus IntegroPectin Revealed by X‐Ray Diffraction, Fourier Transform Infrared, and Nanoparticle Tracking Analysis

open access: yesChemistryOpen, Volume 15, Issue 5, May 2026.
Structural investigation of lemon, orange, and red orange IntegroPectin using X‐ray diffraction, infrared spectroscopy, and nanoparticle tracking analysis unveils several structural nuances of relevance to forthcoming studies on the use of citrus IntegroPectin for therapy and prevention of numerous diseases.
Rosaria Ciriminna   +11 more
wiley   +1 more source

Molecular Detection and Antibiotic Susceptibility Profiling of Mannheimia haemolytica Isolates From Pneumonic Pasteurellosis Suspected Cases of Sheep in Northwestern Ethiopia

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study in Northwestern Ethiopia analysed M. haemolytica in pneumonic sheep and identified 23 M. haemolytica isolates from 140 nasal swab samples. M. haemolytica isolates were sensitive to most drugs, including tetracycline, chloramphenicol, gentamicin, streptomycin, kanamycin and ampicillin.
Fanuel Bizuayehu Yihunie   +6 more
wiley   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra   +10 more
wiley   +2 more sources

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