Results 31 to 40 of about 355,572 (286)

Putrescine supplementation shifts macrophage L-arginine metabolism related-genes reducing Leishmania amazonensis infection.

open access: yesPLoS ONE, 2023
Leishmania is a protozoan that causes leishmaniasis, a neglected tropical disease with clinical manifestations classified as cutaneous, mucocutaneous, and visceral leishmaniasis.
Jonathan Miguel Zanatta   +6 more
doaj   +1 more source

L-Arginine and Hypertension [PDF]

open access: yesThe Journal of Nutrition, 2004
Hypertension is a major healthcare problem afflicting nearly 50 million individuals in the United States. Despite its strong causal association with cardiovascular disease complications including myocardial infarction, heart failure, and stroke, the majority of patients with hypertension do not achieve optimal blood pressure control.
openaire   +2 more sources

Oral or topical administration of L-arginine changes the expression of TGF and iNOS and results in early wounds healing [PDF]

open access: yes, 2016
PURPOSE: To evaluate the contribution of L-arginine oral or topical rout of administration in the surgical wound healing process. METHODS: L-arginine was orally or topically administrated to mice after a laparotomy model procedure.
Almeida, Rosane Mansan de   +10 more
core   +3 more sources

l-Arginine-Dependent Epigenetic Regulation of Interleukin-10, but Not Transforming Growth Factor-β, Production by Neonatal Regulatory T Lymphocytes

open access: yesFrontiers in Immunology, 2017
A growing number of diseases in humans, including trauma, certain cancers, and infection, are known to be associated with l-arginine deficiency. In addition, l-arginine must be supplemented by diet during pregnancy to aid fetal development. In conditions
Kuender D. Yang   +14 more
doaj   +1 more source

Effect of arginine vasopressin on the canine epicardial coronary artery: experiments on V1-receptor-mediated production of nitric oxide

open access: yesArquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To determine whether arginine vasopressin releases endothelium-derived nitric oxide (EDNO) from the epicardial coronary artery. METHODS: We studied segments of canine left circumflex coronary arteries suspended in organ chambers to measure ...
Paulo Roberto B. Evora   +4 more
doaj   +1 more source

Beneficial effects of L-Arginine in patients hospitalized for COVID-19: New insights from a randomized clinical trial

open access: yesPharmacological Research, 2023
We have recently demonstrated in a double-blind randomized trial the beneficial effects of L-Arginine in patients hospitalized for COVID-19. We hypothesize that one of the mechanisms underlying the favorable effects of L-Arginine is its action on ...
Valentina Trimarco   +5 more
doaj   +1 more source

l-Arginine in coronary atherosclerosis

open access: yesInternational Journal of Cardiology, 2000
Nitric oxide is formed from the N-guanido terminal of the amino acid L-arginine and from molecular oxygen by nitric oxide synthase enzymes. L-arginine administration improves the coronary blood flow response to acetylcholine in patients with normal coronary arteries and hypercholesterolemia, reverses the defective endothelium-dependent vasodilation ...
Tentolouris, C   +5 more
openaire   +3 more sources

Endothelium-dependent relaxation in response to poly-L-arginine in canine coronary arteries: implications about hyperpolarization as a mechanism of vasodilatation

open access: yesArquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To study the mechanism by which poly-L-arginine mediates endothelium-dependent relaxation. METHODS: Vascular segments with and without endothelium were suspended in organ chambers filled with control solution maintained at 37ºC and bubbled ...
Paulo R. B. Evora   +4 more
doaj   +1 more source

Effects of L-arginine and L-NAME on ischemia-reperfusion in rat liver [PDF]

open access: yesActa Cirúrgica Brasileira, 2015
PURPOSE: To evaluated the effects of L-arginine (a NO donor) and L-NAME (Nw-nitro-L-arginine methyl ester - a NOS inhibitor) on ischemia-reperfusion in rat livers.METHODS: One hundred fifty two male Wistar rats were divided into four groups: control ...
Márcio Luís Lucas   +4 more
doaj   +1 more source

L-arginine as a novel target for clinical intervention in inflammatory bowel disease

open access: yesExploration of Immunology, 2021
Arginase-1 (Arg1) and the inducible nitric oxide synthase 2 (NOS2) compete for the common substrate L-arginine, semi-essential amino acid, and central intestinal metabolite.
Björn Nüse, Jochen Mattner
doaj   +1 more source

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