Lipids in Health and Disease, 2008 Background The impact of L-arginine on atherogenesis and its ability to prevent endothelial dysfunction have been studied extensively during the past years.
Haghjooyjavanmard Shaghayegh +3 more
doaj +1 more source
Deprivation of L-Arginine Induces Oxidative Stress Mediated Apoptosis in Leishmania donovani Promastigotes: Contribution of the Polyamine Pathway. [PDF]
PLoS Neglected Tropical Diseases, 2016 The growth and survival of intracellular parasites depends on the availability of extracellular nutrients. Deprivation of nutrients viz glucose or amino acid alters redox balance in mammalian cells as well as some lower organisms.
Abhishek Mandal +11 more
doaj +1 more source
Kidney mass reduction leads to L‐arginine metabolism‐dependent blood pressure increase in mice [PDF]
, 2018 Background Uninephrectomy (UNX) is performed for various reasons, including kidney cancer or donation. Kidneys being the main site of L‐arginine production in the body, we tested whether UNX mediated kidney mass reduction impacts L‐arginine metabolism
Fingerhut, Ralph +6 more
core +2 more sources
Serum L-arginine and Dimethylarginine Levels in Migraine Patients with Brain White Matter Lesions [PDF]
, 2016 Background/Aim Migraine is a risk factor for the formation of silent brain white matter lesions (WMLs) that are possibly ischemic in nature. Although dysfunction of the L-arginine/nitric oxide (NO) pathway has been associated with oxidative stress and ...
Bosnyák, Edit +13 more
core +1 more source
Jurnal Neuroanestesi Indonesia, 2019 Preeklampsia mengakibatkan komplikasi pada 3–5% dari seluruh kehamilan. Dihubungkan dengan persalinan prematur, solusio plasenta dan lahir mati serta komplikasi stroke iskemik, stroke perdarahan, edema serebri serta kejang.
Niken Asri Utami, Zafrullah Kany Jasa
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Exogenous NG-hydroxy-l-arginine causes nitrite production in vascular smooth muscle cells in the absence of nitric oxide synthase activity [PDF]
, 1994 Nitric oxide (NO) production from exogenous NG-hydroxy-l-arginine (OH-l-Arg) was investigated in rat aortic smooth muscle cells in culture by measuring nitrite accumulation in the culture medium.
C.A. Schott +26 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The effect of L-arginine on guinea-pig and rabbit airway smooth muscle function in vitro
Brazilian Journal of Medical and Biological Research, 1998 We have investigated the effects of L-arginine, D-arginine and L-lysine on airway smooth muscle responsiveness to spasmogens in vitro. Both L-arginine and D-arginine (100 mM) significantly reduced the contractile potency and maximal contractile response ...
A.C. Perez +4 more
doaj +1 more source
Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME [PDF]
, 2017 AIM: To counteract/reveal celecoxib-induced toxicity and NO system involvement. ----- METHODS: Celecoxib (1 g/kg b.w. ip) was combined with therapy with stable gastric pentadecapeptide BPC 157 (known to inhibit these lesions, 10 μg/kg, 10 ng ...
Bauk, Lara +9 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source