Results 191 to 200 of about 457,288 (287)

Influence of N-Acetyl-L-Cysteine on the Pharmacokinetics and Antibacterial Activity of Marbofloxacin in Chickens. [PDF]

Antibiotics (Basel)
Roydeva A, Rusenova N, Milanova A.
europepmc   +1 more source

Biosynthesis of S-Methyl-L-cysteine and S-Methyl-L-cysteine Sulfoxide from Methionine in Garlic

Chemical and Pharmaceutical Bulletin, 1963
M, SUGII, S, NAGASAWA, T, SUZUKI
openaire   +2 more sources

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

l-Cysteine-Glutathione Mixed Disulfide, a Novel Bioavailable Sulfhydryl-Modified Glutathione Precursor, Protects against Early Liver Injury Induced by Short-Term Hypercholesterolemia. [PDF]

Chem Res Toxicol
Martínez-Gili L, Fucho R, Caballero F, Núñez S, Jaara HS, Alarcón-Vila C, Rico N, Nagasawa HT, García-Ruiz C, Fernández-Checa JC, Torres S.   +10 more
europepmc   +1 more source

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

Effect of N-Acetyl-L-Cysteine (NAC) on Inflammation After Intraperitoneal Mesh Placement in an <i>Escherichia coli</i> Septic Rat Model: A Randomized Experimental Study. [PDF]

Med Sci (Basel)
Parpoudi S, Mantzoros I, Ioannidis O, Zapsalis K, Gamali T, Kyziridis D, Gekas C, Anestiadou E, Symeonidis S, Bitsianis S, Kotidis E, Pramateftakis MG, Miliaras D, Bikouli A, Iosifidis G, Angelopoulos S.   +15 more
europepmc   +1 more source

Adsorption Dynamics and Self-Assembled L-cysteine on Au(100) [PDF]

, 2014
Engelbrekt, Christian, Mao, Bingwei, Nazmutdinov, Renat R., Ulstrup, Jens, Yan, Jiawei, Zhang, Jingdong, Zinkicheva, T. T.   +6 more
core  

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

N-acetyl-L-cysteine improves mitochondrial and oxidative defects in the acadian variant of fanconi syndrome. [PDF]

Exp Biol Med (Maywood)
Al-Younis I, Martín-Jiménez R, Khan M, Baussan Y, Jose C, Thibeault Y, Hebert-Chatelain E.   +6 more
europepmc   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source