Results 31 to 40 of about 457,288 (287)

L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice

open access: yesFrontiers in Molecular Neuroscience, 2019
We have reported previously that L-cysteine-derived hydrogen sulfide (H2S) demonstrates a remarkable neuroprotective effect against hypoxia-ischemic (HI) insult in neonatal animals.
Xin Zhou   +12 more
doaj   +1 more source

Lifespan extension and increased resistance to environmental stressors by N-Acetyl-L-Cysteine in Caenorhabditis elegans

open access: yesClinics, 2015
OBJECTIVE: This study was performed to determine the effect of N-acetyl-L-cysteine, a modified sulfur-containing amino acid that acts as a strong cellular antioxidant, on the response to environmental stressors and on aging in C. elegans.
Seung-Il Oh   +2 more
doaj   +1 more source

Electrochemical behaviour of N-acetyl-l-cysteine on gold electrode—A tentative reaction mechanism [PDF]

open access: yes, 2007
The electrochemical behaviour of N-acetyl-l-cysteine (NAC) has been investigated by linear and cyclic voltammetry on gold electrode at room temperature. The results showed two oxidation peaks under acid and neutral conditions and only one in basic medium.
Barus, Carole   +4 more
core   +2 more sources

Effects of Sulfur Amino Acids on Tyrosyl or Serine/Threonine Phosphorylation and Translocation of Cytosolic Compounds to Cell Membrane in Stimulus-treated Human Neutrophils [PDF]

open access: yes, 2009
We investigated the effects of various sulfur amino acids on the phosphorylation of proteins and the translocation of cytosolic compounds to cell membrane in stimulus-treated human neutrophils using specific monoclonal antibodies.
Abe, Hidehiro   +6 more
core   +1 more source

Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress

open access: yesRedox Biology, 2017
Neonatal hypoxic-ischemic (HI) injury is a major cause of neonatal death and neurological dysfunction. H2S has been shown to protect against hypoxia-induced injury and apoptosis of neurons. L-Cysteine is catalyzed by cystathionine-β-synthase (CBS) in the
Song Liu   +10 more
doaj   +1 more source

Bioavailability of Organosulfur Compounds after the Ingestion of Black Garlic by Healthy Humans

open access: yesAntioxidants, 2023
The consumption of black garlic has been related to a decreased risk of many human diseases due to the presence of phytochemicals such as organosulfur compounds (OSCs).
Alicia Moreno-Ortega   +4 more
doaj   +1 more source

Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages. [PDF]

open access: yesPLoS ONE, 2014
N-acetyl-L-cysteine is known to act as a reactive oxygen species scavenger and used in clinical applications. Previous reports have shown that high-dose N-acetyl-L-cysteine treatment inhibits the expression of proinflammatory cytokines in activated ...
Tomokazu Ohnishi   +4 more
doaj   +1 more source

Functional characterization and structure-guided mutational analysis of the transsulfuration enzyme cystathionine γ-lyase from toxoplasma gondii [PDF]

open access: yes, 2018
Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite Toxoplasma gondii includes the genes for cystathionine β-synthase and cystathionine γ-lyase (TgCGL), as well as for cysteine synthase, which are crucial enzymes ...
Astegno, A.   +6 more
core   +2 more sources

Determination of L-cysteine Based on its Potentiometric Effect on a Belousov-Zhabotinskii Oscillating Chemical Reaction

open access: yesInternational Journal of Electrochemical Science, 2011
Here, a simple and convenient method with suitable selectivity and high sensitivity for the determination of L-cysteine based on Belousov-Zhabotinskii (B-Z) oscillating chemical reaction is presented.
Jahan-Bakhsh Raoof   +4 more
doaj   +1 more source

The endogenous production of hydrogen sulphide in intrauterine tissues [PDF]

open access: yes, 2009
Background: Hydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE).
Carson, Ray J.   +4 more
core   +5 more sources

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