Results 41 to 50 of about 457,288 (287)

Hypoxia releases S-nitrosocysteine from carotid body glomus cells—relevance to expression of the hypoxic ventilatory response

Frontiers in Pharmacology, 2023
We have provided indirect pharmacological evidence that hypoxia may trigger release of the S-nitrosothiol, S-nitroso-L-cysteine (L-CSNO), from primary carotid body glomus cells (PGCs) of rats that then activates chemosensory afferents of the carotid ...
James M. Seckler, Paulina M. Getsy, Walter J. May, Benjamin Gaston, Santhosh M. Baby, Tristan H. J. Lewis, James N. Bates, Stephen J. Lewis, Stephen J. Lewis, Stephen J. Lewis   +9 more
doaj   +1 more source

An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein [PDF]

, 2005
Campylobacter jejuni is a Gram-negative food-borne pathogen associated with gastroenteritis in humans as well as cases of the autoimmune disease Guillain Barre syndrome. C.
Altekruse, Anthony J. Wilkinson, Axel Müller, Brown, Bryant, Burguiere, Deka, Delaney, During-Olsen, Elena Blagova, Emsley, Fukami-Kobayashi, Gavin H. Thomas, Gouet, Harris, Holland, Hosie, Hosie, James A. Brannigan, Jones, Kaldor, Kazwala, Keith S. Wilson, Kelly, Kertesz, Kraulis, Levdikov, Magnusson, Mark J. Fogg, Martin, Merrell, Merritt, Miller, Murshudov, Newberry, Newcomer, Oh, Oh, Olsen, Palmer, Parkhill, Pawelec, Pawelec, Pei, Pei, Perrakis, Pittman, Richard Horler, Rosef, Schonheyder, Sun, Svedhem, Takahashi, Terwilliger, Vagin, Vargas, Velayudhan, Vladimir M. Levdikov, Walter, Wilkinson, Wyszynska, Yao   +61 more
core   +1 more source

Voltammetric Determination of Butyl Hydroxy Anisd Based on the Enhanced Effect of Gold Nanorods Assembled on a Poly-L-cysteine Film Electrode

International Journal of Electrochemical Science, 2016
Polymerization of L-cysteine was performed on a glassy carbon electrode surface using cyclic voltammetric scanning from -0.2 V to 2.0 V. After being immersed in a gold nanorods solution over one night, a gold nanorod modified poly-L-cysteine film ...
Yinghua Deng, Kaiping Luo, Guishen Liu, Xiaodong Hou, Yina Huang, Chunya Li   +5 more
doaj   +1 more source

Cysteine transport through excitatory amino acid transporter 3 (EAAT3). [PDF]

PLoS ONE, 2014
Excitatory amino acid transporters (EAATs) limit glutamatergic signaling and maintain extracellular glutamate concentrations below neurotoxic levels. Of the five known EAAT isoforms (EAATs 1-5), only the neuronal isoform, EAAT3 (EAAC1), can efficiently ...
Spencer D Watts, Delany Torres-Salazar, Christopher B Divito, Susan G Amara   +3 more
doaj   +1 more source

Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. [PDF]

, 2010
One of the major hurdles for the development of gene therapy for Fanconi anemia (FA) is the increased sensitivity of FA stem cells to free radical-induced DNA damage during ex vivo culture and manipulation.
Adair, J, Beard, BC, Becker, PS, Chien, S, Kiem, H-P, Kohn, DB, Shimamura, A, Taylor, JA, Trobridge, GD, Wagner, JE, Zhao, X   +10 more
core   +2 more sources

Distribution of D-amino acids in vinegars and involvement of lactic acid bacteria in the production of D-amino acids [PDF]

, 2013
Levels of free D-amino acids were compared in 11 vinegars produced from different sources or through different manufacturing processes. To analyze the D- and L-amino acids, the enantiomers were initially converted into diastereomers using pre-column ...
Hirofumi Akano, Katsumi Doi, Taketo Ohmori, Toshihisa Ohshima, Yuta Mutaguchi   +4 more
core   +1 more source

Escherichia coli Uses Separate Enzymes to Produce H2S and Reactive Sulfane Sulfur From L-cysteine

Frontiers in Microbiology, 2019
Hydrogen sulfide (H2S) has been proposed to have various physiological functions, and it may function through reactive sulfane sulfur. Since the two sulfur forms often coexist, they are normally considered interchangeable.
Kai Li, Yufeng Xin, Guanhua Xuan, Rui Zhao, Huaiwei Liu, Yongzhen Xia, Luying Xun, Luying Xun   +7 more
doaj   +1 more source

Extraction and Activity of O-acetylserine(thiol)lyase (OASTL) from Microalga Chlorella sorokiniana [PDF]

, 2017
O-acetylserine(thiol)lyase (OASTL) is an enzyme catalysing the reaction of inorganic sulphide with O-acetylserine to form the S-containing amino acid L-cysteine.
Carfagna, Simona, Salbitani, Giovanna
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Neuroprotective Roles of l-Cysteine in Attenuating Early Brain Injury and Improving Synaptic Density via the CBS/H2S Pathway Following Subarachnoid Hemorrhage in Rats

Frontiers in Neurology, 2017
l-Cysteine is a semi-essential amino acid and substrate for cystathionine-β-synthase (CBS) in the central nervous system. We previously reported that NaHS, an H2S donor, significantly alleviated brain damage after subarachnoid hemorrhage (SAH) in rats ...
Gang Li, Zhen Wang, Tong Li, Tong Li, Lingxiao Wang, Lingxiao Wang, Quan Hu, Quan Hu, Song Liu, Xuemei Bai, Yunkai Xie, Tiantian Zhang, Shishi Bo, Xiangqian Gao, Shuhua Wu   +14 more
doaj   +1 more source