Results 81 to 90 of about 13,238,937 (304)

Serum L-DOPA levels.

open access: yes, 2015
(A) Time-course of serum L-DOPA levels after last L-DOPA administration at dose 5 mg/kg (day 10) with co-injection of 1.25 mg/kg carbidopa (n = 5 per AAV2-hAADC or AAV2-GFP group) and without carbidopa co-injection (n = 5 per AAV2-hAADC or AAV2-GFP group)
Nitasha Sharma (720396)   +4 more
core   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

open access: yesAdvanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang   +7 more
wiley   +1 more source

L-DOPA Ropes in tRNAPhe [PDF]

open access: yes, 2011
L-DOPA is the most commonly prescribed drug for the treatment of Parkinson's disease. Here, Moor et al. (2011) report that phenylalanyl-tRNA synthetase catalyzes the misacylation of tRNAPhe by L-DOPA, suggesting that it may contribute to the elevated ...
Eric A. First, First, Eric A.
core   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

open access: yesAdvanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou   +10 more
wiley   +1 more source

The role of L-DOPA in plants [PDF]

open access: yesPlant Signaling & Behavior, 2014
Since higher plants regularly release organic compounds into the environment, their decay products are often added to the soil matrix and a few have been reported as agents of plant-plant interactions. These compounds, active against higher plants, typically suppress seed germination, cause injury to root growth and other meristems, and inhibit ...
Anderson Ricardo, Soares   +5 more
openaire   +2 more sources

O papel da dopamina no desenvolvimento de fadiga em modelo experimental de doença de Parkinson [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2013A doença de Parkinson (DP) é a segunda doença neurodegenerativa mais prevalente na população, com maior
Scheffer, Débora da Luz
core  

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

open access: yesAdvanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li   +7 more
wiley   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu   +12 more
wiley   +1 more source

A Multiscale Mechanistic Framework for Polydopamine Dyeing in Ultrablack Wool Textiles

open access: yesAdvanced Science, EarlyView.
Ultrablack photonic textiles are enabled through polydopamine (PDA) dyeing, which is governed by the interplay of PDA chemistry, wool surface topology and chemistry, and hierarchical fiber–yarn–fabric architecture. Fabric architecture emerges as a primary and previously underappreciated design lever for wide‐angle optical performance.
Hansadi Jayamaha   +4 more
wiley   +1 more source

Temporal administration of entacapone with slow release L-dopa: pharmacokinetic profile and clinical outcome

open access: yes, 2004
Entacapone is a specific, peripherally acting catechol- O-methyltransferase (COMT) inhibitor that prevents peripheral degradation of L-dopa, thus improving its bioavailability.
A. Bassi   +22 more
core   +1 more source

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