Results 1 to 10 of about 11,930 (298)

Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase. [PDF]

PLoS ONE, 2010
3,4-Dihydroxyphenylalanine decarboxylase (DDC), also known as aromatic L-amino acid decarboxylase, catalyzes the decarboxylation of a number of aromatic L-amino acids.
Qian Han, Haizhen Ding, Howard Robinson, Bruce M Christensen, Jianyong Li   +4 more
doaj   +2 more sources

Evidence that tyrosine hydroxylase does not have enzymatic activity in neurons of the supraoptic nucleus [PDF]

Frontiers in Endocrinology
IntroductionAlthough numerous neurons expressing tyrosine hydroxylase (TH), the first enzyme of catecholamine synthesis, were discovered in the supraoptic nucleus (SON) of hypothalamus in animals almost forty years ago, mainly under osmotic stress, the ...
Tatiana S. Pronina, Dmitry V. Troshev, Anna A. Kolacheva, Vsevolod V. Bogdanov, Michael V. Ugrumov   +4 more
doaj   +2 more sources

Beyond Melanin: Proteomics Reveals Virulence-Related Proteins in Paracoccidioides brasiliensis and Paracoccidioides lutzii Yeast Cells Grown in the Presence of L-Dihydroxyphenylalanine

Journal of Fungi, 2020
Species of the genus Paracoccidioides cause a systemic infection in human patients. Yeast cells of Paracoccidioides spp. produce melanin in the presence of L-dihydroxyphenylalanine and during infection, which may impact the pathogen’s survival in the ...
Rodrigo Almeida-Paes, Marcos Abreu Almeida, Lilian Cristiane Baeza, Leticia Andrade Mendes Marmello, Monique Ramos de Oliveira Trugilho, Joshua Daniel Nosanchuk, Celia Maria de Almeida Soares, Richard Hemmi Valente, Rosely Maria Zancopé-Oliveira   +8 more
doaj   +2 more sources

Multi-molecular imaging showing tumour heterogeneity and differing diagnostic performance in a case with metastatic pheochromocytoma [PDF]

EJNMMI Reports
A patient with multiple endocrine neoplasia 2A (MEN2A) and a suspicion of metastasized pheochromocytoma, underwent multi-molecular positron emission tomography (PET) imaging with the recently presented radiopharmaceutical [18F]-metafluorobenzylguanidine (
Fredrik Hedeer, Jenny Oddstig, Páll Hallgrimson, Katarina Fagher   +3 more
doaj   +2 more sources

Proximate composition and anti-nutritional factors in Mucuna pruriens (velvet bean) seed flour as affected by several processing methods

Heliyon, 2023
Mucuna pruriens seed being an underutilized legume with antinutrients was processed to reduce antinutrients and improve nutritional quality. The seeds were cleaned, washed and subjected to single treatments of soaking (24 h, 48 h, 72 h), cooking (20 min,
Clement Chinedum Ezegbe, Justina Nne Nwosu, Clifford Ifeanyi Owuamanam, Tope Adeyemisi Victor-Aduloju, Smith G. Nkhata   +4 more
doaj   +1 more source

Enzymatic polymerization of enantiomeric L−3,4-dihydroxyphenylalanine into films with enhanced rigidity and stability

Nature Communications, 2023
L−3,4-dihydroxyphenylalanine is an important molecule in the adhesion of mussels, and as an oxidative precursor of natural melanin, it plays an important role in living system.
Yuhe Shen, Rongxin Su, Dongzhao Hao, Xiaojian Xu, Meital Reches, Jiwei Min, Heng Chang, Tao Yu, Qing Li, Xiaoyu Zhang, Yuefei Wang, Yuefei Wang, Wei Qi   +12 more
doaj   +1 more source

Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate

Journal of Pharmacological Sciences, 2023
Methylphenidate (MPH) and methamphetamine (METH) are the current treatments of choice for attention deficit/hyperactivity disorder. We previously reported that METH induces the release of dopamine (DA) and of the neurotransmitter candidate L-3,4 ...
Hiraku Uchimura, Kaori Kanai, Masami Arai, Miyu Inoue, Akitoyo Hishimoto, Daiki Masukawa, Yoshio Goshima   +6 more
doaj   +1 more source

Novel Strecker degradation products of tyrosine and dihydroxyphenylalanine

Czech Journal of Food Sciences, 2001
Tyrosine was oxidised with either potassium peroxodisulphate or glyoxal. Volatile reaction products were isolated and analysed by GC/FID and GC/MS, derivatised with diazomethane and analysed by the same methods.
J. Adamiec, K. Cejpek, J. Rössner, J. Velíšek   +3 more
doaj   +1 more source

Biomedical and Clinical Importance of Mussel-Inspired Polymers and Materials

Marine Drugs, 2015
The substance secreted by mussels, also known as nature’s glue, is a type of liquid protein that hardens rapidly into a solid water-resistant adhesive material.
Nagendra Kumar Kaushik, Neha Kaushik, Sunil Pardeshi, Jai Gopal Sharma, Seung Hyun Lee, Eun Ha Choi   +5 more
doaj   +1 more source

Effects of Aging on Levo-Dihydroxyphenylalanine- Induced Dyskinesia in a Rat Model of Parkinson’s Disease

Frontiers in Aging Neuroscience, 2021
BackgroundIt remains unclear why patients with young-onset Parkinson’s disease more often develop levo-dihydroxyphenylalanine (L-dopa)-induced dyskinesia (LID) and have a more severe form than patients with old-onset Parkinson’s disease. Previous studies
Haruo Nishijima, Tamaki Kimura, Fumiaki Mori, Koichi Wakabayashi, Iku Kinoshita, Takashi Nakamura, Tomoya Kon, Chieko Suzuki, Masahiko Tomiyama   +8 more
doaj   +1 more source