Efficient production of salvianic acid A from l-dihydroxyphenylalanine through a tri-enzyme cascade
Salvianic acid A (SAA), used for treating cardiovascular and cerebrovascular diseases, possesses several pharmacological properties. However, the current methods for the enzymatic synthesis of SAA show low efficiency.
Jiahui Yang +9 more
doaj +1 more source
Rheology and Gelation of Hyaluronic Acid/Chitosan Coacervates
Hyaluronic acid (HA) and chitosan (CHI) are biopolyelectrolytes which are interesting for both the medical and polymer physics communities due to their biocompatibility and semi-flexibility, respectively.
A. Basak Kayitmazer +3 more
doaj +1 more source
Ferreascidin: A highly aromatic protein containing 3,4-dihydroxyphenylalanine from the blood cells of a stolidobranch ascidian [PDF]
A method of isolation and purification was developed for the major protein from the blood cells of the stolidobranch ascidian Pyura stolonifera. The protein, called ferreascidin because of its strong iron binding capacity (two Fe3+ per molecule), is the ...
Lavin, Martin F. +6 more
core +1 more source
Amyloid deposits are insoluble fibrous protein aggregates, identified in numerous diseases, which self-assemble through molecular recognition. This process is facilitated by short amino acid sequences, identified as minimal modules.
Galit Fichman +3 more
doaj +1 more source
Silk composites with natural rubber (NR) were prepared by mixing degummed silk and NR latex solutions. A significant enhancement of the mechanical properties was confirmed for silk/NR composites compared to a NR-only product, indicating that silk can be ...
Hiromitsu Sogawa +3 more
doaj +1 more source
Chronic continuous and intermittent l-3,4-dihydroxyphenylalanine treatments differentially affect basal ganglia function in 6-hydroxydopamine lesioned rats-an autoradiographic study using [3H]flunitrazepam [PDF]
The effects of chronic 'continuous' and 'intermittent' l-3,4-dihydroxyphenylalanine treatments on GABA receptor function in the basal ganglia of rats with unilateral 6-hydroxydopamine lesions of the medial forebrain bundle was investigated, by ...
Robertson, R. G., Gnanalingham, K. K.
core +1 more source
Isolation of 3,4-dihydroxyphenylalanine-containing proteins using boronate affinity chromatography [PDF]
A rapid procedure for the isolation of 3,4-dihydroxyphenylalanine-containing proteins has been developed in which the protein is selectively bound to a m-phenylboronate agarose column, and eluted with 1.0 m ammonium acetate, pH 3.0.
Lavin, Martin F. +3 more
core +1 more source
Constructing Optical Biosensor Based on Multienzyme System Tyrosinase/Horseradish Peroxidase [PDF]
By using sol-gel method, hybrid membranes were synthesized based on SiO2 and cellulose derivatives. Membranes showed good physical and mechanical properties as well as good biocompatibility.
Lyubov Yotova, Spaska Yaneva
doaj +2 more sources
Radical sequestration by protein-bound 3,4-dihydroxyphenylalanine [PDF]
Protein-bound 3,4-dihydroxyphenylalanine (PB-DOPA), a redox-active product of protein oxidation, is capable of functioning as both a pro- and antioxidant.
Foxwell, Alice R. +3 more
core +3 more sources
Synthesis of the Isodityrosine Moiety of Seongsanamide A–D and Its Derivatives
The concise and highly convergent synthesis of the isodityrosine unit of seongsanamide A–D and its derivatives bearing a diaryl ether moiety is described.
Yang Xie +7 more
doaj +1 more source

