Results 151 to 160 of about 10,236,148 (357)

Continuous Apomorphine Infusion in Multiple System Atrophy Real‐World Insights From a French Nationwide Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Continuous subcutaneous apomorphine infusion (CSAI) is effective in Parkinson's disease but has not been evaluated in multiple system atrophy (MSA). Objective To assess the 6‐month efficacy and tolerability of CSAI in MSA patients. Methods French multicenter retrospective registry‐based analysis of CSAI use in MSA.
Simon Lamy, Frederique Leh, Alexandra Foubert‐Samier, Soizic Leguy Bonnet, Guillaume Baille, Margherita Fabbri, Margaux Dunoyer, Lise Mantisi, Caroline Giordana, Anaïs El Ouartassi, Olivier Rascol, Wassilios G. Meissner, David Bendetowicz, Marie Vanel, David Grabli, Fabienne Ory‐Magne, Sophie Drapier   +16 more
wiley   +1 more source

Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano, Carolina Gorodetsky, Darcia Paul, Jürgen Germann, Aaron Loh, Han Yan, Peter L. Carlen, Sara Breitbart, Andres M. Lozano, George M. Ibrahim, Suneil K. Kalia   +10 more
wiley   +1 more source

Levodopa is associated with reduced development of new-onset geographic atrophy in patients with age-related macular degeneration

Eye and Vision
Background Geographic atrophy (GA) is a significant cause of vision loss in patients with age-related macular degeneration (AMD). Current treatments are limited to anti-complement drugs, which have limited efficacy to delay progression with significant ...
Kyle S. Chan, Nitika Aggarwal, Shannon Lawson, Nick Boucher, Mathew W. MacCumber, Jeremy A. Lavine   +5 more
doaj   +1 more source

Effect of pyridoxal phosphate deficiency on aromatic L-amino acid decarboxylase activity with L-dopa and L-5-hydroxytryptophan as substrates in rats.

, 1982
Mohammed Khalilur Rahman, Toshiharu Nagatsu, Tae SAKURAI, Seiji Hori, M. Abe, Makoto Matsuda   +5 more
openalex   +1 more source

Peripheral Aromatic L-Amino Acids Decarboxylase Inhibitor in Parkinsonism. I. EFFECT ON O-METHYLATED METABOLITES OF L-DOPA-2-14C [PDF]

, 1972
F.S. Messiha, T. H. Hsu, J. R. Bianchine
openalex   +1 more source

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch, Athena Mancini, Adham Elsherbini, Jason Yuen, Andres Lozano   +4 more
wiley   +1 more source

Measuring L-dopa in plasma and urine to monitor therapy of elderly patients with Parkinson disease treated with L-dopa and a dopa decarboxylase inhibitor

, 1993
We have established a method for measuring L-dopa in plasma and urine, including the metabolites dopamine and L-dopac, using separation by ion-pair reversed-phase HPLC and quantification with an electrochemical detector.
Copeland, L G, Roberts, N B, Playfer, J R, Dutton, J   +3 more
core  

Pitx3Null Mutant (Striatal Dopamine-Deficient) Mice Have Exaggerated Spiny Projection Neuron Responses to l-DOPA and D1 Agonism and Lack Baseline Striatonigral Spiking

, 2017
Ben Sagot
openalex   +1 more source

The clinical efficacy of L-DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus [PDF]

, 2011
Alessandro Stefani, Ernesto Fedele, Jerrold L. Vitek, Mariangela Pierantozzi, Salvatore Galati, F Marzetti, Antonella Peppe, Mario Stampanoni Bassi, Giorgio Bernardi, Paolo Stanzione   +9 more
openalex   +1 more source

Multimodal Treatment of Neck Pain in Multiple System Atrophy

Movement Disorders Clinical Practice, EarlyView.
Bianca Caliò, Svenja Schmidt, Alessandra Fanciulli   +2 more
wiley   +1 more source