Results 131 to 140 of about 39,473 (264)

Interactions of the Tricyclic Antidepressant Drug Amitriptyline with L-DOPA in the Nucleus Accumbens, Prefrontal Cortex and Hippocampus of Unilaterally 6-OHDA-Lesioned Rats: Relevance to Depression in Parkinson's Disease. [PDF]

Biomolecules
Kamińska K, Lenda T, Konieczny J, Lorenc-Koci E.   +3 more
europepmc   +1 more source

Males are worse mothers: Comparing care patterns in a facultatively caring beetle

Insect Science, EarlyView.
Why should biparental care exist if offspring fare just as well when only one parent is present? In the facultatively dependent burying beetle, Nicrophorus vespilloides, manipulating environmental quality reveals that biparental care benefits offspring in form of lower personal immune requirement and parents in term of weight gain.
Leon Müller, Patrick Limburg, Maximilian Körner   +2 more
wiley   +1 more source

L-Dopa Comparably Improves Gait and Limb Movements in Parkinson's Disease: A Wearable Sensor Analysis. [PDF]

Biomedicines
Zampogna A, Pietrosanti L, Saggio G, Patera M, Falletti M, Bellia V, Fattapposta F, Costantini G, Suppa A.   +8 more
europepmc   +1 more source

L-DOPA-therapy in Parkinson's disease: some personal reflections on L-DOPA therapy from Vienna and Berlin. [PDF]

J Neural Transm (Vienna), 2023
Riederer P, Horowski R.
europepmc   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Pregnenolone Reduces L-Dopa-Induced Dyskinesias in Female Parkinsonian Monkeys. [PDF]

Mov Disord
Bourque M, Morissette M, Bortolato M, Frau R, Carta M, Di Paolo T.   +5 more
europepmc   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Remodeling of Perineuronal Nets in the Striato-Cortical Axis in L-DOPA-Induced Dyskinesia Rat Model. [PDF]

Int J Mol Sci
Bilbay NT, Tel BC, Akkus G, Cakir-Aktas C, Solakoglu T, Yalcin-Cakmakli G, Elibol B.   +6 more
europepmc   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, EarlyView.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Agaricus arvensis extract-coated functionalized silver nanoparticles for effective aerobic biotransformation of synthetic L-tyrosine to L-DOPA. [PDF]

AMB Express
Li Y, Ali S, Khan QF, Ahmad MU, Fatima L, Shah TA, Assefa M, Al-Emam A.   +7 more
europepmc   +1 more source